1.
Org Lett
; 8(19): 4367-70, 2006 Sep 14.
Article
in English
| MEDLINE
| ID: mdl-16956228
ABSTRACT
A new family of air- and moisture-stable phosphine-phosphoramidite ligands (PEAPhos) has been prepared from commercially available and inexpensive (S)-alpha-phenylethylamine through a two- or three-step transformation and successfully applied in the rhodium-catalyzed enantioselective hydrogenations of a variety of substrates, in which up to 99.9% ee was obtained for all of these kinds of substrates.