Subject(s)
Bone Neoplasms/pathology , Frontal Bone , Osteoma/pathology , Paranasal Sinus Neoplasms/pathology , Adult , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/surgery , Diagnosis, Differential , Female , Humans , Neoplasm Invasiveness , Osteoma/diagnostic imaging , Osteoma/surgery , Otorhinolaryngologic Surgical Procedures/methods , Paranasal Sinus Neoplasms/diagnostic imaging , Paranasal Sinus Neoplasms/surgery , Tomography, X-Ray ComputedSubject(s)
Empyema/diagnosis , Frontal Sinus , Orbit , Paranasal Sinus Diseases/diagnosis , Skull , Cysts , Diagnosis, Differential , Empyema/complications , Empyema/surgery , Female , Humans , Magnetic Resonance Imaging , Middle Aged , Otorhinolaryngologic Surgical Procedures/methods , Paranasal Sinus Diseases/complications , Paranasal Sinus Diseases/surgery , Tomography, X-Ray ComputedABSTRACT
A new technique for endolaryngeal microsurgery is proposed. It based on the irradiation of benign laryngeal tumours using Ho:YAG and potassium-titanyl-phosphate (KTP) lasers. A total of 198 patients of either sex aged from 2 to 77 years with a variety of benign laryngeal neoplasms were treated by this method between 2004 and 2007. Its application allowed the results of the treatment to be optimized as confirmed by the statistically significant improvement of the external respiration function, acoustic characteristics of the voice, and positive dynamics of laryngeal endoscopic imaging data.
Subject(s)
Endoscopy/methods , Forced Expiratory Volume/physiology , Laser Therapy/methods , Microsurgery/methods , Pharyngeal Neoplasms/surgery , Voice/physiology , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Follow-Up Studies , Humans , Lasers, Solid-State/therapeutic use , Male , Middle Aged , Pharyngeal Neoplasms/physiopathology , Retrospective Studies , Treatment Outcome , Young AdultSubject(s)
Laryngostenosis/etiology , Tuberculosis, Laryngeal/complications , Antitubercular Agents/therapeutic use , Diagnosis, Differential , Humans , Laryngoscopy/methods , Laryngostenosis/diagnosis , Laryngostenosis/therapy , Male , Middle Aged , Tracheostomy/methods , Tuberculosis, Laryngeal/diagnosis , Tuberculosis, Laryngeal/therapySubject(s)
Nose Neoplasms/diagnosis , Sarcoma, Kaposi/diagnosis , Adult , Biopsy , Diagnosis, Differential , Female , Humans , Laser Therapy/methods , Magnetic Resonance Imaging , Nose Neoplasms/surgery , Otorhinolaryngologic Surgical Procedures/methods , Sarcoma, Kaposi/surgery , Tomography, X-Ray ComputedSubject(s)
Brain Diseases/diagnosis , Mucormycosis/diagnosis , Rhinitis/diagnosis , Antifungal Agents/therapeutic use , Biopsy , Brain Diseases/microbiology , Brain Diseases/therapy , Diagnosis, Differential , Drainage/methods , Female , Humans , Middle Aged , Mucorales/isolation & purification , Mucormycosis/microbiology , Mucormycosis/therapy , Rhinitis/microbiology , Rhinitis/therapy , Tomography, X-Ray ComputedSubject(s)
Nasal Polyps/pathology , Turbinates/pathology , Adolescent , Female , Humans , Magnetic Resonance Imaging , Nasal Polyps/surgery , Punctures , Turbinates/surgerySubject(s)
Bone Neoplasms/diagnostic imaging , Bone Neoplasms/pathology , Chondrosarcoma, Mesenchymal/diagnostic imaging , Chondrosarcoma, Mesenchymal/pathology , Maxillary Neoplasms/diagnostic imaging , Maxillary Neoplasms/pathology , Adult , Bone Neoplasms/surgery , Chondrosarcoma, Mesenchymal/surgery , Endoscopy , Female , Humans , Maxillary Neoplasms/surgery , Neoplasm Staging , Tomography, X-Ray ComputedSubject(s)
Chondroma/surgery , Laryngeal Neoplasms/surgery , Aged , Chondroma/pathology , Female , Humans , Laryngeal Neoplasms/pathologySubject(s)
Ethmoid Sinus/pathology , Fibroma/complications , Fibroma/pathology , Fibrosarcoma/complications , Fibrosarcoma/pathology , Maxillary Neoplasms/complications , Maxillary Neoplasms/pathology , Nasopharyngeal Neoplasms/complications , Nasopharyngeal Neoplasms/pathology , Paranasal Sinus Neoplasms/complications , Paranasal Sinus Neoplasms/pathology , Sphenoid Sinus/pathology , Adult , Combined Modality Therapy , Ethmoid Sinus/radiation effects , Ethmoid Sinus/surgery , Female , Fibroma/therapy , Fibrosarcoma/therapy , Humans , Maxillary Neoplasms/therapy , Nasopharyngeal Neoplasms/therapy , Paranasal Sinus Neoplasms/therapy , Sphenoid Sinus/radiation effects , Sphenoid Sinus/surgery , Treatment OutcomeABSTRACT
An original method of wedge dehydration of biological fluids assessing the ability for separation of organic and mineral constituents was for the first time used in patients with different forms of chronic tonsillitis (CT). The method was used in 102 patients aged 8-68 years with chronic inflammation of the palatine tonsils out of exacerbation. A dehydrated drop of tonsillar lacuna discharge (TLD), facia, was studied morphologically under microscope at small magnification (x10--x50). Three types of TLD facia were identified in CT patients. These types characterized severity of the pathological process in the palatine tonsils. Changes of facia type in patients with different CT forms were compared. Basic regularities in the disease progress were determined. This enabled prognosis of a further course of CT in an individual patient and, therefore, planning treatment policy for each case.
Subject(s)
Tonsillitis/pathology , Tonsillitis/therapy , Adolescent , Adult , Aged , Child , Chronic Disease , Female , Humans , Male , Middle Aged , Prognosis , Severity of Illness Index , Tonsillitis/diagnosis , Treatment OutcomeABSTRACT
It is shown that staged individual special respiratory exercises targeted at nervous-muscular apparatus of the pharynx and trachea improve external respiration function, activate blood flow and venous-lymphatic outflow in the neck area with stimulation of reparative processes in combined postoperative treatment of patients with cicatricial stenoses of the pharynx and trachea.
Subject(s)
Exercise Therapy , Laryngostenosis/therapy , Tracheal Stenosis/therapy , Adolescent , Adult , Aged , Female , Humans , Male , Middle AgedABSTRACT
BACKGROUND: CD69 is a surrogate marker of T-cell responsiveness to mitogen and Ag stimulus and can be used as a measure of T-lymphocyte activation. Quantitative flow cytometric determination of CD69 expression on T lymphocytes has several advantages over traditional lymphocyte proliferation assays, but this method has not yet been standardized for clinical applications. METHODS: We qualified a commercially available assay using the manufacturer's procedures for measurement of T-cell response to a mitogen (PHA), superantigen (Staphylococcus endotoxin B; SEB) and Ca(2+) ionophore (phorbyl myristate acetate; PMA) with peripheral blood from healthy volunteers. Following this, we tested the usefulness of the assay in determining T-cell responses to PHA and SEB for six immunocompromised patients. RESULTS: Healthy volunteers showed 17-fold increases in T-cell CD69 Ab bound per cell (ABC) with PHA stimulation compared with the baseline. SEB was also an effective T-cell activating agent, increasing CD69 ABC by 5-fold, comparable with results obtained with PMA stimulation. PHA- and SEB-stimulated T-cell CD69 ABC for patients 100 days post-BM transplant were generally below 1 SD of that from healthy volunteers. SEB-stimulated T-cell CD69 expression was significantly depressed for CD8(+) T cells while CD4(+) T-cell responses to SEB were generally within 1 SD of the mean for healthy volunteers. DISCUSSION: These results suggest that quantitative measurement of CD69 surface expression by flow cytometry is a useful diagnostic tool for detailed assessment of T-lymphocyte and subset activation.
Subject(s)
Antigens, CD/metabolism , Antigens, Differentiation, T-Lymphocyte/metabolism , Flow Cytometry/methods , T-Lymphocytes/immunology , Bone Marrow Transplantation , Flow Cytometry/standards , Humans , Immunocompromised Host/immunology , Lectins, C-Type , Lymphocyte Activation/drug effects , Lymphocyte Activation/immunology , Mitogens/pharmacology , Reproducibility of Results , T-Lymphocytes/metabolism , Time FactorsSubject(s)
Cyclophosphamide/therapeutic use , Granulomatosis with Polyangiitis/diagnosis , Granulomatosis with Polyangiitis/therapy , Prednisolone/therapeutic use , Administration, Cutaneous , Biopsy , Cyclophosphamide/administration & dosage , Diagnosis, Differential , Drug Therapy, Combination , Follow-Up Studies , Glucocorticoids/administration & dosage , Glucocorticoids/therapeutic use , Humans , Immunosuppressive Agents/administration & dosage , Immunosuppressive Agents/therapeutic use , Injections, Intravenous , Laryngoscopy/methods , Male , Middle Aged , Plasmapheresis/methods , Radiography, ThoracicABSTRACT
Based on their 40 years' clinical experience in treating patients with laryngeal and cervical tracheal stenoses of various etiology, the authors consider that circular trachectomy, by anastomosing laryngeal cartilages, may be performed by highly skilled specialists only at specialized and well-equipped institutions. In cases of chondroperichondritis of cartilages of the larynx or trachea in the presence of paralysis of the vocal folds, it is necessary to make stepwise reparative and plastic operations that can be performed at the ENT clinics having experience in laryngeal surgery.
Subject(s)
Laryngostenosis/surgery , Otorhinolaryngologic Surgical Procedures/methods , Tracheal Stenosis/surgery , Humans , Treatment OutcomeABSTRACT
The anatomy of the tip of the nose is reviewed with description of clinical manifestations in different variants of anatomical structures of the tip of the nose. Thick skin problem and specific features of surgical treatment of nasal tip deformities in thick, porous skin are considered.
