ABSTRACT
A highly effective oxidative thiyl radical addition/cyclization of N-methacryloylbenzamides was explored using dioxygen as the sole terminal oxidant without the use of precious and/or toxic transition-metal catalysts. This method provides convenient access to a variety of useful sulfide-containing 4,4-disubstituted isoquinoline-1,3-diones by constructing C-S and C-C bonds in one step.
ABSTRACT
In the title compound, C(18)H(16)N(4)O(4), the dihedral angles between the central pyrazole ring and the pendant substituted and unsubstituted aromatic rings are 4.73â (12) and 44.24â (14)°, respectively. An intra-molecular O-Hâ¯O hydrogen bond occurs. In the crystal structure, an inter-molecular C-Hâ¯O inter-action may help to consolidate the packing and a short intra-molecular C-Hâ¯O contact also occurs.
ABSTRACT
The title Schiff base compound, C(14)H(10)Cl(2)N(2), crystallizes with one half-mol-ecule in the asymmetric unit. The mid-point of the N-N bond [1.418â (3)â Å] lies on an inversion centre. The mol-ecular skeleton is approximately planar, the largest deviation from the mean plane being 0.143â (4)â Å for the N-bonded C atom. The crystal packing exhibits no classical inter-molecular hydrogen bonds.