1.
Org Lett
; 24(28): 5029-5033, 2022 07 22.
Article
in English
| MEDLINE
| ID: mdl-35822841
ABSTRACT
This method represents an efficient rhodium(III)-catalyzed o-C-H arylation of readily available benzimidate derivatives with diverse arylsilanes in water as a sustainable solvent, enabling the straightforward synthesis of potentially useful biphenyl-2-carbonitrile derivatives. This silicon-based protocol employs benzimidates as both an efficacious directing group and the source of a nitrile group.