ABSTRACT
The development of paraffin-selective adsorbents is desirable but extremely challenging because adsorbents usually prefer olefin over paraffin. Herein, a new pore-window-partition strategy is proposed for the rational design of highly efficient paraffin-preferred metal-organic framework (MOF) adsorbents. The power of this strategy is demonstrated by stepwise installations of linear bidentate N-donor linkers into a prototype MOF (SNNU-201) to produce a series of partitional MOF adsorbents (SNNU-202-204). With continuous pore-window partitions from SNNU-201 to SNNU-204, the isosteric heat of adsorption can be tuned from -34.4 to -19.4 kJ mol-1 for ethylene and from -25.5 to -20.7 kJ mol-1 for ethane. Accordingly, partitional MOFs exhibit much higher ethane adsorption capacities, especially for SNNU-204 (104.6 cm3 g-1), representing nearly 4 times as much ethane as the prototypical counterpart (SNNU-201; 27.5 cm3 g-1) under ambient conditions. The C2H6/C2H4 ideal adsorbed solution theory selectivity, dynamic breakthrough experiments, and theoretical simulations further indicate that pore-window partition is a promising and universal strategy for the exploration of highly efficient paraffin-selective MOF adsorbents.
ABSTRACT
OBJECTIVE: To study the relationship between peripheral blood hepatocellular carcinoma cells-associated AFP mRNA and tumor relapse and metastasis. METHODS: To detect several blood samples from the HCC patients by nested RT-PCR to find out AFP mRNA after 24 h, 72 h and one week and 4 weeks after surgery, and followed up the HCC patients for 1, 2, 3 years. RESULTS: There were 7 patients occurred relapse or distant metastasis in 12 patients with AFP mRNA positive (7/12, 58.3%), there were 5 patients occurred relapse in 19 patients with AFP mRNA negative (5/19, 26.3%) within 1 year, there was 4 patients occurred relapse in second year (9/19, 47.3%); 5 patients occurred relapse in third year (10/19, 52.6%). Obvious connection between patients AFP mRNA positive and AFP mRNA negative was observed (P < 0.01). CONCLUSIONS: HCC with AFP mRNA positive has more change to be recurrent compared with HCC patients with AFP mRNA negative.
