Effect of Dynamic High-Pressure Microfluidization on the Quality of Not-from-Concentrate Cucumber Juice.

The effects of dynamic high-pressure microfluidization (DHPM at 400 MPa) and heat treatment (HT) on the microbial inactivation, quality parameters, and flavor components of not-from-concentrate (NFC) cucumber juice were investigated. Total aerobic bacteria, yeasts and molds were not detected in the 400 MPa-treated cucumber juice. Total phenolic content increased by 16.2% in the 400 MPa-treated cucumber juice compared to the control check (CK). The significant reduction in pulp particle size (volume peak decreasing from 100-1000 µm to 10-100 µm) and viscosity increased the stability of the cucumber juice while decreasing the fluid resistance during processing. HT decreased the ascorbic acid content by 25.9% (p < 0.05), while the decrease in ascorbic acid content was not significant after 400 MPa treatment. A total of 59 volatile aroma substances were identified by gas chromatography-ion mobility spectrometry (GC-IMS), and a variety of characteristic aroma substances (i.e., valeraldehyde, (E)-2-hexenal, (E)-2-nonenal, and (E,Z)-2,6-nonadienal, among others) were retained after treatment with 400 MPa. In this study, DHPM technology was innovatively applied to cucumber juice processing with the aim of providing a continuous non-thermal processing technology for the industrial production of cucumber juice. Our results provide a theoretical basis for the application of DHPM technology in cucumber juice production.

Transition-metal-free radical difluorobenzylation/cyclization of unactivated alkenes: access to ArCF2-substituted ring-fused quinazolinones.

A mild and efficient transition-metal-free radical difluorobenzylation/cyclization of unactivated alkenes toward the synthesis of difluorobenzylated polycyclic quinazolinone derivatives with easily accessible α,α-difluoroarylacetic acids has been developed. This transformation has the advantages of wide functional group compatibility, a broad substrate scope, and operational simplicity. This methodology provided a highly attractive access to pharmaceutically valuable ArCF2-containing polycyclic quinazolinones.

Pensamiento filosófico médico sobre la obesidad / Medical philosophical rational on obesity

Introducción: La ciencia y la tecnología son importantes para el progreso histórico con sus consecuencias inevitables para el desarrollo social. Uno de los componentes de la ciencia y la tecnología que sigue la misma ley y se desarrolla de manera proporcional al desarrollo de la sociedad son las ciencias médicas. Su función es proteger, cuidar, desarrollar y mejorar los recursos y la calidad de la fuerza laboral, y promover el desarrollo social. Por lo tanto, es una condición necesaria que influye directamente en la reproducción humana y garantiza el desarrollo económico y social. Los servicios médicos socialistas son servicios productivos y de bienestar, que mejoran la fuerza física y la inteligencia, además crean condiciones favorables para el desarrollo social y económico e interactúan con la sociedad. Objetivo: Demostrar la influencia de los avances de la ciencia y la tecnología en la salud humana y la atención primaria y describir la importancia de concebir al hombre como un ser biopsicosocial en la atención primaria de salud y la prevención de obesidad. Métodos: Se realiza un estudio de revisión a través de las referencias bibliográficas actualizadas sobre el tema. Desarrollo: China también ha propuesto pautas específicas para la prevención de la obesidad, pero los resultados son pobres. Por un lado, esto está relacionado con la gran tasa de población del país, y por otro, con el lento desarrollo de la atención médica primaria y la falta de concientización sobre la importancia de prevenir el sobrepeso y la obesidad como estrategia de trabajo. Conclusiones: Los profesionales de la salud deben crear estrategias adaptadas a las condiciones locales, de forma tal que perciban una buena atmósfera para controlar el peso. Esto aumentara la conciencia de la sociedad, respecto al problema de la obesidad(AU)

ABSTRACT Introduction: Science and technology are important for historical progress with its inevitable consequences for social development. One of the components of science and technology that follows the same law and advances in proportion to the development of society are the medical sciences. Its function is to protect, to care for, to develop and to improve the resources and quality of the workforce, and to promote social development. Therefore, it is a necessary condition that directly influences human reproduction and guarantees economic and social development. Socialist medical services are productive and welfare services, which improve physical strength and intelligence, also create favorable conditions for social and economic development and interact with society. Objective: To prove the influence of advances in science and technology on human health and primary care and describe the importance of conceiving man as a biopsychosocial being in primary health care and obesity prevention. Methods: A review study is carried out through updated bibliographic references on the subject. Findings: China has also proposed specific guidelines for obesity prevention, but the results are poor. On the one hand, this is related to the high population rate in the country, and on the other, to the slow development of primary medical care and the lack of awareness of the importance of preventing overweight and obesity as a work strategy. Conclusions: Health professionals must create strategies adapted to local conditions, in such a way that they perceive good atmosphere to control weight. This will increase the awareness of society(AU) regarding the obesity problem.

Sobrepeso y obesidad en la autopercepción corporal de adultos en China / Overweight and obesity in adult body self-perception in China

Introducción: En China la prevalencia del sobrepeso y obesidad está aumentando de manera vertiginosa. Objetivo: Valorar la autopercepción corporal de los adultos chinos y determinar su relación con los indicadores antropométricos. Métodos: Se realizó un estudio observacional de corte transversal en Panzhihua, China. La muestra estuvo conformada por n = 151 sujetos, con edades comprendidas entre los 18 y 80 años que cumplieron con los criterios de inclusión establecidos. Se les realizó cuestionario a través de una entrevista presencial y mediciones del peso, talla, circunferencia de la cintura y de la cadera, determinaciones del índice de masa corporal, índice de circunferencia de la cintura y la de cadera y el porcentaje de grasa corporal. Resultados: Según la clasificación del porcentaje de grasa corporal se determinó normopeso (10,6 por ciento), 28,5 por ciento con sobrepeso y 60,9 por ciento con obesidad. De acuerdo con el índice de masa corporal se encontró en el nivel delgado (5,3 por ciento), 47,0 por ciento normopeso, 32,5 por ciento en sobrepeso y 15,2 por ciento obesos. Según el índice de circunferencia de la cintura y la de cadera, 34,4 por ciento fue normal y 65,6 por ciento presentó obesidad abdominal. La autopercepción corporal: 54,7 por ciento de los sujetos se autopercibieron como normopeso, 24,3 por ciento tenían una percepción de sobrepeso y 12,2 por ciento se autopercibió obeso. Las correlaciones entre la autopercepción corporal, el índice de masa corporal y el porcentaje de grasa corporal expresaron diferencia significativa (p ;0,05), la autopercepción corporal y el índice de circunferencia de la cintura y la de cadera no evidenció diferencia (p> 0,05). Según la correlación de Pearson, el porcentaje de grasa corporal fue más confiable como indicador. Conclusión: La autopercepción corporal de los sujetos en esta investigación no fue adecuada. El porcentaje de grasa corporal fue el indicador antropométrico más confiable del estudio(AU)

Introduction: In China, the prevalence of overweight and obesity is increasing dramatically. Objective: To assess the body self-perception of Chinese adults and to determine their relationship with anthropometric indicators. Methods: An observational cross-sectional study was conducted in Panzhihua, China. The sample was made up of n = 151 subjects, aged between 18 and 80 years who met the established inclusion criteria. A questionnaire was conducted through a face-to-face interview and measurements of weight, height, waist and hip circumference, determinations of the body mass index, waist circumference index and that of the hip and the percentage of body fat. Results: According to the classification of the body fat percentage, it was determined 10.6 percent normal weight, 28.5 percent overweight and 60.9 percent obesity. According to the body mass index, it was found 5.3 percent in the thin level, 47.0 percent normal weight, 32.5 percent overweight and 15.2 percent obese. According to the waist and hip circumference index, 34.4 percent was normal and 65.6 percent had abdominal obesity. Regarding body self-perception, 54.7 percent of the subjects self-perceived as normal weight, 24.3 percent considered themselves to be overweight and 12.2 percent self-perceived as obese. The correlations between body self-perception, body mass index and body fat percentage expressed a significant difference (p;0.05), body self-perception and the waist and hip circumference index showed no difference (p;0.05). According to the Pearson correlation, the percentage of body fat was more reliable as an indicator. Conclusion: The body self-perception of the subjects in this research was not adequate. Body fat percentage was the most reliable anthropometric indicator in the study(AU)

[Study on the interaction of genistein and human serum albumin by spectroscopic method].

The interaction of genistein and human serum albumin (HSA) was investigated by fluorescence quenching spectra, synchronous fluorescence spectra and ultra-violet absorption spectra. The results showed that the quenching mechanism of the intrinsic fluorescence of HSA by genistein is due to the formation of genistein-HSA complex, resulting in a static quenching procedure. The binding constants (KA) were 1.00 x 10(6) (27 degrees C), 1.66 x 10(6) (37 degrees C) and 5.25 x 10(6) (47 degrees C), respectively. According to the Förster theory of non-radiation energy transfer, the binding distances (r) were 2.59 nm (27 degrees C), 2.65 nm (37 degrees C) and 2.90 nm (47 degrees C), respectively. The thermodynamic parameters showed that the binding power between genistein and HSA is mainly the electrostatic interaction Synchronous spectrum was used to investigate the conformational change of HSA.