1.
Chem Commun (Camb)
; 51(58): 11564-7, 2015 Jul 25.
Article
in English
| MEDLINE
| ID: mdl-26076660
ABSTRACT
A novel copper-catalyzed [3+2] cycloaddition reaction of secondary amines with α-diazo compounds has been developed via a cross-dehydrogenative coupling process. The reaction involves a sequential aerobic oxidation/[3+2] cycloaddition/oxidative aromatization procedure and provides an efficient method for the construction of 1,2,3-triazoles in a single step in an atom-economic manner from readily available starting materials under very mild conditions.