The relationship between mindfulness and suboptimal health status: a chain/serial mediation model.

Background: Suboptimal health status (SHS) represents a third state between health and disease and often progresses into chronic conditions, negatively impacting an individual's well-being. Studies have shown that mindfulness has a beneficial effect on various SHS symptoms. This study aims to explore the influence of mindfulness on SHS and its underlying mechanisms, with a particular focus on examining the mediating roles of stress and social support. Methods: A total of 173 healthy Chinese college or graduate students, with an average age of 21.85 years, participated in this study. Measurements were taken using the Five Factor Mindfulness Questionnaire, the Sub-Health Measurement Scale, the Perceived Stress Scale, and a self-constructed scale that included demographic information. The PROCESS plugin for SPSS was used to assess mediating effects. Results: Significant correlations were found among SHS, social support, mindfulness, and perceived stress (|r| = 0.38-0.85, p < 0.01). Specifically, mindfulness showed a significant positive correlation with SHS and social support (r = 0.38-0.77), while perceived stress was significantly negatively correlated with mindfulness, social support, and SHS (|r| = 0.45-0.85). Perceived social support was positively associated with SHS (r = 0.65). Furthermore, social support and perceived stress partially mediated the influence of mindfulness on SHS. Additionally, a sequential mediation effect of perceived social support and stress in the relationship between mindfulness and SHS was supported. Conclusion: The cultivation of trait mindfulness may be advantageous for individuals' sub-health. Perceived social support and perceived stress are important underlying mechanisms contributing to this effect.

Silver nanoparticles deposited carbon microspheres nanozyme with enhanced peroxidase-like catalysis for colorimetric detection of Hg2+ in seafood.

Novel methods for high-performance detection of Hg2+ in seafood are critical for ensuring food safety and human health. Herein, Ag nanoparticles (Ag NPs) were successfully deposited on carbon microspheres (CMs) to form Ag NPs-CMs nanocomplex. The proposed Ag NPs-CMs could oxidize colorless 3,3',5,5'-tetramethylbenzidine (TMB) to blue oxidation state TMB (oxTMB) in the presence of hydrogen peroxide (H2O2) and had a significant UV-vis absorption peak at 652 nm. The excellent peroxidase-like activity was attributed to the increased electrostatic attraction of CMs and the catalytic synergistic effect. After adding Hg2+, the catalytic activity of Ag NPs-CMs was specifically enhanced and the Michaelis-Menten constant (Km) decreased from 0.067 to 0.052 mmol/L due to the formation of Ag-Hg amalgam which produced more superoxide anions (O2•-) and hydroxyl radicals (•OH). The linear response ranges for Hg2+ were 2~833 nmol/L and 2.5~40 µmol/L, with the low detection limit of 1.10 nmol/L. This method was applied to detect Hg2+ in seafood with satisfactory recoveries of 95.65~106.56%. A hydrogel kit was designed for portable detection of Hg2+, and the response range was 0.5~5 µmol/L. This work provides a reliable method for visual Hg2+ detection in seafood as well as a feasible strategy for the design of high-performance nanozymes.

The Relationship between Perfectionism and Social Anxiety: A Moderated Mediation Model.

Social anxiety is one of the mental health problems associated with perfectionism. The present study investigated the possible mediation of perceived stress in the relationship between perfectionism and social anxiety, and whether this mediation depends on the level of trait mindfulness. A total of 425 college students (female: 82.9%; mean age: M = 19.90 ± 1.06 years old) completed the Multidimensional Perfectionism Scale (MPS), the Chinese Perceived Stress Scale (CPSS), the Interaction Anxiousness Scale (IAS), and the Five-Facet Mindfulness Questionnaire (FFMQ). After controlling for age and gender, the moderated mediation analysis suggested that perfectionism significantly and positively predicted social anxiety and that perceived stress mediated the link between perfectionism and social anxiety. In addition, the indirect effect of perfectionism on social anxiety was moderated by trait mindfulness. Specifically, the indirect effect was weaker among the individuals with a high level of mindfulness compared to those with a low level of mindfulness. The findings of this study suggest that trait mindfulness significantly moderates the indirect effect of perfectionism on social anxiety via perceived stress.

Self-propelled nanomotors based on hierarchical metal-organic framework composites for the removal of heavy metal ions.

The outstanding performance efficiency for the removal of heavy metal ions in solution is governed by various factors: (a) sufficient contact probability between heavy metal ions and the adsorbent, (b) convenient diffusion/accessibility of heavy metal ions to the surface and the interior of the adsorbent, and (c) abundant binding sites for heavy metal ions on the adsorbent. We designed an efficient MnFe2O4 @MIL-53 @UiO-66 @MnO2 adsorbent for Pb(II) and Cd(II) removal. The adsorbents were fabricated by merging self-propelled nanomotors, exploiting hierarchical structure, and using a metal-organic framework (MOF) composite to simultaneously meet the three requirements. The sufficient contact probability between Pb(II)/Cd(II) and MnFe2O4 @MIL-53 @UiO-66 @MnO2 was achieved via the self-propelled movement of MnFe2O4 @MIL-53 @UiO-66 @MnO2 which was induced by the catalytic decomposition of H2O2 by MnO2. The convenient diffusion/accessibility of Pb(II)/Cd(II) on the surface and interior of MnFe2O4 @MIL-53 @UiO-66 @MnO2 was achieved by exploiting the properties of the hierarchical structure of MnFe2O4 @MIL-53 @UiO-66 @MnO2. Abundant binding sites (-COOH) on MIL-53 and UiO-66 composites were present for the binding of the Pb(II)/Cd(II) ions to the adsorbent. The adsorption capacities of the nanomotor adsorbent for Pb(II) and Cd(II) were 1018 and 440.8 mg g-1 at 25 °C, respectively. Additionally, the complex formed of MnFe2O4 and MIL-53 endowed the adsorbent with easy-recyclable properties under the influence of an external magnet. The nanomotors exhibit satisfactory removal performances for Pb(II) and Cd(II).

UiO-67 decorated on porous carbon derived from Ce-MOF for the enrichment and fluorescence determination of glyphosate.

A nanocomposite was prepared by loading UiO-67 nanoparticles onto porous carbon materials derived from Ce-MOF (Ce-PC) for fluorescence detection of glyphosate. The probe (UiO-67/Ce-PC) exhibits fluorescence emission at 414 nm as the response signal under excitation at 310 nm. The fluorescence enhancement mode of UiO-67 reduces the background interference, and the introduction of Ce-PC provide hierarchical nanostructure and large specific surface area that can increase the contact availability and improve the pre-enrichment effect, ensuring UiO-67/Ce-PC with superior sensitivity. The abundant metal hydroxyl group (M-O-H) of UiO-67/Ce-PC could recognize phosphoryl groups (-PO3H2) of glyphosate through ligand exchange, which synergizes with H-bonding interaction and electrostatic attraction to exhibit specificity toward glyphosate. The competitive coordination effects weaken the ligand-to-metal charge transfer (LMCT) and consequently induce the fluorescence recovery. The calibration plot of the fluorescence enhancement response of UiO-67/Ce-PC towards glyphosate was recorded in the range 0.02-30 µg mL-1 with a low limit of detection (LOD) of 0.0062 µg mL-1, which is superior to the pure UiO-67. In addition, the sensor exhibited high selectivity and satisfactory accuracy and precision with recoveries of 92.1-105.6% and RSDs below 3.4%. This work not only presents a feasible sensor for sensitive and selective determination of glyphosate from cereal samples, but also provides a promising strategy for the design of MOF-based nanocomposites to achieve trace detection of various pollutants.

Interface engineering of zeolite imidazolate framework-8 on two-dimensional Al-metal-organic framework nanoplates enhancing performance for simultaneous capture and sensing tetracyclines.

The increasing misgivings of environmental pollution derived from antibiotic residues make it imperative to explore a bifunctional platform for synchronous monitoring and removal of antibiotics. Herein, zeolite imidazolate framework-8 (ZIF-8) is anchored on two-dimensional (2D) amino-functionalized Al-metal organic framework (NH2-MIL-53(Al)) nanoplates to construct a dual metal-organic frameworks smart platform (ZIF-8/NH2-MIL-53(Al)) for simultaneous capture and fluorescence sensing of tetracyclines (TCs). ZIF-8 nanoparticles anchored on 2D nanoplates having a smaller size and a larger specific surface area boost the adsorption capabilities (561, 533, 526 and 578 mg g-1 for doxycycline (DOX), tetracycline (TET), oxytetracycline (OTC) and chlortetracycline (CTC), respectively). Notably, the pyridine N of ZIF-8 cooperated with the abundant NH2 on the surface of NH2-MIL-53(Al) exhibits high affinity toward TCs, remarkably enhancing the sensitivity by facilitating the photo-induced electron transfer and the inner-filter effect. The LODs (1.2 µg L-1 for TET, DOX, OTC and 2.2 µg L-1 for CTC, respectively) are at least 10-fold lower than those of NH2-MIL-53(Al) and are comparable or superior to those of reported sensors. The dual metal-organic frameworks smart platform presents satisfactory reliabilities and accuracies for detecting TCs in real samples, which anticipates new routes to develop integrated systems for simultaneous capture and detection of organic pollutants.

Amino-Functionalized Al-MOF for Fluorescent Detection of Tetracyclines in Milk.

A fluorescent method for detection of tetracyclines (TCs) in milk was developed by using the NH2-MIL-53(Al) nanosensor synthesized via a one-pot hydrothermal method. The nanosensor had a crystalline nanoplates structure with rich groups of -NH2 and -COOH. The -NH2/-COOH of NH2-MIL-53(Al) reacted with the -CO-/-OH of TCs to form a complex. The electron of -NH2/-COOH from the NH2-BDC ligand transferred to the -CO-/-OH of TCs. -NH2 of the NH2-MIL-53(Al) interacted with the -CO-/-OH of TCs by hydrogen bonding. The quenching efficiency of the inner filter effect (IFE) was calculated to contribute 57-89%. The synergistic effect of photoinduced electron transfer (PET) and IFE account for fluorescence quenching. TCs were quantitatively detected in milk samples with recoveries of 85.15-112.13%; the results were in great accordance with high-performance liquid chromatography (HPLC) ( P > 0.05), confirming the NH2-MIL-53(Al) nanosensor has potential applicability for the detection of TCs in food matrix.