Bariatric surgery to aLleviate OCcurrence of Atrial Fibrillation Hospitalization-BLOC-AF.

BACKGROUND: Obesity is associated with a higher incidence of atrial fibrillation (AF). Weight reduction improves outcomes in patients known to have AF. OBJECTIVE: The purpose of this study was to compare the incidence of heart failure (HF) or first-time AF hospitalization in obese patients undergoing bariatric surgery (BAS) vs other abdominal surgeries. METHODS: A retrospective cohort study was conducted using linked hospital discharge records from 1994-2014. Obese patients without known AF or atrial flutter (AFL) who had undergone abdominal hernia or laparoscopic cholecystectomy surgery were identified for each case that underwent BAS (2:1). Clinical outcomes were HF, first-time hospitalization for AF, AFL, gastrointestinal bleeding (GIB), and ischemic or hemorrhagic stroke. Outcomes were analyzed using conditional proportional hazard modeling accounting for the competing risk of death, adjusting for demographics and comorbidities. RESULTS: There were 1581 BAS cases and 3162 controls (48% age <50 years; 60% white; 79% female; mean CHA2DS2VASc score 1.6 ± 1.2) with follow-up of 66 months. Compared to controls, BAS cases had a significantly lower risk of new-onset AF (hazard ratio [HR] 0.71; 95% confidence interval [CI] 0.54-0.93) or HF (HR 0.74; 95% CI 0.60-0.91) but a higher risk of GIB (HR 2.1; 95% CI 1.5-3.0), with no differences in AFL, ischemic stroke, or hemorrhagic stroke. Reduction in AF improved as follow-up increased beyond 60 months. CONCLUSION: In patients undergoing BAS, the risk of either HF or AF was reduced by ∼29% but with greater risk of GIB. The findings support the hypothesis that weight loss reduces the long-term risk of HF or incident AF hospitalization.

Patient Perception of the Remote Versus Clinic Visits for Interrogation of Implantable Cardioverter Defibrillators.

Implantable Cardioverter Defibrillators (ICDs) are used in the management of sudden cardiac arrest. Compared with clinic visits, remote interrogation of these devices has shown clinical benefit and lower cost. We hypothesize that demographic and socioeconomic factors influence patient satisfaction with remote monitoring and therefore the choice of a pathway for follow-up. Questionnaires were mailed to 85 patients (mean age 63 ± 13.5 years, 73% male), with ICDs implanted for primary prevention of sudden cardiac arrest. Information regarding education, social support, employment, and income was collected. To compare clinic and remote monitoring, patients were given questionnaires to assess which parameters they consider important: convenience, accuracy, human contact, scheduling, and cost. Of the 34 responders, patients rated clinic visit to be as accurate with better opportunity to ask questions and better human contact, but there was no difference in perception of convenience, scheduling, or cost between the 2 groups. Significant number of patients dropped from the labor market after ICD implantation; however labor status, education, or income did not influence the preference of clinic appointment. Survey respondents preferred clinic to remote interrogation because they believe clinic appointments allow better interaction. Educating patients about the benefits of remote interrogation and improved communication will enhance utilization of this sophisticated technology for superior patient care.

Comparison of Cryoballoon and Hybrid surgical Posterior Wall Isolation for Persistent Atrial Fibrillation to conventional ablation.

BACKGROUND: Optimalablation strategy for persistent atrial fibrillation (AF) is unclear;PWI of the left atrium may improve outcome.Our aim was to compare outcomes of posterior wall isolation (PWI) ablation for persistent AF achieved by cryoballoon ablation (CRYO) or hybrid surgical ablation (HABL) to matched patients undergoing conventional radiofrequency ablation (CRA). METHODS: In our single center retrospective study,patients underwent HABL and CRYO withcircumferential pulmonary vein ablation (CPVA),roof and floor lines to complete PW box lesion. CRA consisted of CPVA, roof line and lateral mitral isthmus line (MVI). RESULTS: Of 61 patients (mean duration of AF 1.3 ± 0.4 yrs)who underwent ablation, after follow-up of 366 ± 62 days, AF recurrence was 10.5% and 48% (p=0.001) and the need for repeat ablation 5% vs 30% (p=0.007) in PWI and CRA groups respectively, without a significant difference in incidence of AT/FL 18 vs 26 % or cardioversion 5.2 vs 7.1 %. Total procedure time and fluoroscopic time were 242 ±70 min vs 279 ±53 min (p=0.08) and 20±9 min vs 12 ± 4 min (p=0.003) for PWI and CRA respectively. CRYO had less AF recurrence and complications than HABL. Mean length of stayfor CRYO patients was 41 hrs compared to 145 hrs in HABL group, who underwent two procedures. CONCLUSION: PWI in persistent AF patients decreases recurrence of AF and need for repeat procedure compared to CRA; PWI by CRYO is superior to HABL due to less LOS and complications.

Gamma Knife Surgery for Cavernous Sinus Hemanginoma: A Report of 32 Cases.

BACKGROUND: Cavernous sinus hemangioma (CSH) is a rare type of benign vascular tumor. Microsurgery for CSH treatment usually results in profuse bleeding and cranial nerve injury. Radiosurgery is an alternative treatment for CSH. The objective of this study was to elucidate the efficacy and safety of gamma knife surgery (GKS) for the treatment of CSH. METHODS: A total of 32 patients with CSH underwent 34 times of GKS as a primary and exclusive treatment from 2009 to 2015 at West China Hospital. The diagnosis was mainly based on findings of magnetic resonance imaging. The treatment was performed with the Leksell Gamma Knife model C. The follow-up period was from 12-67 months. Changes in imaging results and signs or symptoms were analyzed. Studies of patients who had undergone radiosurgery and microsurgery were compared. RESULTS: Clinical improvement was observed after GKS in 26 of 27 patients who presented with signs or symptoms of CSH. Tumor shrinkage was detected in all cases. A reduction in tumor volume of 0-25%, 26%-50%, 51%-75%, and 76%-100% was observed in 3, 2, 8, and 19 cases, respectively. Remarkable tumor shrinkage occurred within 6-12 months after GKS. According to a retrospective analysis of 151 patients diagnosed with CSH, 77 patients underwent GKS without any complications, 17 of 74 patients were treated with microsurgery and exhibited persistent complications, and 1 patient died. CONCLUSIONS: GKS is a safe and effective treatment for most cases of CSH. The concept of GKS as an adjuvant treatment for CSH requires reconsideration.