1.
Eksp Klin Farmakol
; 62(4): 30-2, 1999.
Article
in Russian
| MEDLINE
| ID: mdl-10513332
ABSTRACT
It was shown on a model of long-term stress induced by chronic electrostimulation of the ventromedial hypothalamus of rabbits that administration of isothiorbamin in the active periods of the experiment prevents hyperactivation of lipid peroxidation in the blood and myocardium by maintaining the activity of antioxidant enzymes. Isothiorbamin also causes an antiatherogenic effect on the blood lipid spectrum, raises the efficacy of the work of the heart and decreases the stressogenic ischemic disorders of the myocardium.