ABSTRACT
The specific features of an infectious process were studied in 150 children treated for mucoviscidosis at the State Pulmonology Research Center, Ministry of Health and Medical Industry of the Russian Federation. Hemophilic bacilli, Staphylococcus aureus, and Pseudomonas aeruginosa were fond to play the leading role in the etiology of the infectious process in the bronchopulmonary system. Pneumococcal infection was first ascertained to be important in the course of the disease. Developmental stages of a pyoinfectious process from the onset of its contamination, acute infection to chronic one were followed up. The most severe, prognostically unfavourable course of the disease was demonstrated to be associated with Pseudomonas aeruginosa infection.
Subject(s)
Bacterial Infections/complications , Cystic Fibrosis/complications , Adolescent , Age Factors , Bacterial Infections/etiology , Bacterial Infections/microbiology , Child , Child, Preschool , Haemophilus Infections/complications , Humans , Infant , Prognosis , Pseudomonas Infections/complications , Staphylococcal Infections/complicationsABSTRACT
In the determination of the etiology of acute bronchitis in children, a complex of microbiological and immunological methods should be used. The isolation of Streptococcus pneumoniae and Haemophilus influenzae at a concentration of greater than or equal to 10(4) cels/ml from tracheobronchial washings is the early and most significant method for the determination of the etiology and therapy of acute bronchitis. On the basis of microbiological and immunobiological criteria, the etiological role of S. pneumoniae has been determined in 78% of patients and that of H. influenzae, in 48% of patients, mainly in association with pneumococci.
Subject(s)
Bronchitis/immunology , Acute Disease , Antibodies, Bacterial/analysis , Bronchitis/diagnosis , Bronchitis/etiology , Child, Preschool , Enterobacteriaceae/immunology , Fluorescent Antibody Technique , Haemophilus influenzae/immunology , Humans , Infant , Pseudomonas aeruginosa/immunology , Streptococcus pneumoniae/immunology , Time FactorsABSTRACT
In the microbiological examination of 132 children aged 0-3 years with acute bronchitis, Streptococcus pneumoniae and Haemophilus influenzae at a concentration of greater than or equal to 10(4) cells/ml, as well as different species of opportunistic bacteria, were isolated from tracheobronchial washings obtained from 100 of these children. S. pneumoniae and H. influenzae were found to play the leading role in the etiology of the acute bacterial inflammatory process in acute bronchitis in children.
