Clinical and transmission dynamics characteristics of 406 children with coronavirus disease 2019 in China: A review.

OBJECTIVE: Chinese pediatricians are working on the front line to fight COVID-19. They have published a great amount of first-hand clinical data. Collecting their data and forming a large sample for analysis is more conducive to the recognition, prevention and treatment of coronavirus disease 2019 in children. The epidemic prevention and control experience of Chinese pediatricians should be shared with the world. METHODS: By searching Chinese and English literature, the data of 406 children with COVID-19 in China were analyzed. RESULTS: It was found that the clustered incidence of children's families is a dynamic transmission feature; the incidence is low; asymptomatic infections and mild cases account for 44.8%, with only 7 cases of critical illness; laboratory examination of lymphocyte counts is not reduced, as it is for adults; chest CT findings are less severe than those for adults. These presentations are the clinical features of COVID-19 in children. Only 55 of the 406 cases were tested by anal swab for virus nucleic acid, 45 of which were positive, accounting for 81.8% of stool samples. CONCLUSION: There are more children than adults with asymptomatic infections, milder conditions, faster recovery, and a better prognosis. Some concealed morbidity characteristics also bring difficulties to the early identification, prevention and control of COVID-19. COVID-19 screening is needed in the pediatric fever clinic, and respiratory and digestive tract nucleic acid tests should be performed. Efforts should be made to prevent children from becoming a hidden source of transmission in kindergartens, schools or families. Furthermore, China's experience in treating COVID-19 in children has led to faster recovery of sick children.

Effectiveness evaluation on the mode of Improving Mood-Promoting Access To Collaborative Treat-ment (IMPACT) for late-life depression / 上海预防医学

To discuss the effectiveness of the IMPACT mode for late-life depression . [ Methods] From Shanghai Pudong mental health network system , 60 cases of elderly depressions were cho-sen according to the criteria for case reqirement .Of the 60 cases , 30 were allocated into the intervention group who were treated with 18 months'IMPACT.The other 30 were included in the control group , who were treated with routine management for psychiatric rehabilitation .Depressive symptoms and medication compli-ance scores were compared and assessed at 6,12 and 18 months before and after intervention by using the hamilton depression scale ( HAMD) , self-rating depression scale ( SDS ) and the insight and treatment atti-tude questionnaire ( ITAQ) .Comparison was also made in re-hospitalization during intervention between the two groups .The patients'quality of life was analyzed and compared between the two groups by 36-items short form health survey (SF-36). [Results] The HAMD and SDS scores in intervention group were signifi-cantly lower than those in control group at 6,12 and 18 months after intervention (Pall<0.05).ITAQ scores were higher than those in control group (P<0.05).According to the SF-36 scores, the bodily pain, general health, vitality, social functioning and mental health scores in intervention group were extremely higher than those in control group (Pall<0.05).There was not one case of recurrence in intervention group , however, there were 6 cases of recurrence in the control group , the recurrence hospitalization rate being 20%(χ2 =6.67, P<0.05). [Conclusion] IMPACT mode for late-life depression could relieve depressive symptoms effectively , thus reducing the recurrence hospitalization rate and improving the quality of life for patients .