ABSTRACT
The informal processing of electronic waste or e-waste contributes to the release of high concentrations of transition metals into the ambient air. The damage caused by chromium, nickel and manganese exposure on lung function in school children from an e-waste recycling area and the role of oxidative stress in this process were evaluated. We recruited school children (n=144, 8-13 years) from an e-waste recycling area in China compared with the control. Spirometry was performed to assess lung function status. The blood levels of chromium, nickel and manganese, antioxidant enzyme activities and lipid peroxidation of the subjects were examined. The concentrations of blood manganese (bMn) and serum nickel (sNi) in the exposed group were significantly higher than those in controls for all three age groups. The forced vital capacity value of boys aged 8-9 years was significantly lower than that of the control. Malondialdehyde levels and superoxide dismutase activities increased significantly in children aged 8-9 years from e-waste environment, but catalase activities declined. School children from an e-waste recycling area were exposed to high levels of the three transition metals. The accumulation of bMn and sNi may be risk factors for oxidative damage and decreased pulmonary function.
Subject(s)
Electronics , Environmental Exposure , Environmental Pollutants/toxicity , Lung/drug effects , Metals/toxicity , Recycling , Adolescent , Catalase/blood , Child , Female , Humans , Lipid Peroxidation , Lung/physiology , Male , Malondialdehyde/metabolism , Manganese/blood , Oxidative Stress , Respiratory Function Tests , Superoxide Dismutase/bloodABSTRACT
Toxic heavy metals are released to the environment constantly from unregulated electronic waste (e-waste) recycling in Guiyu, China, and thus may contribute to the elevation of lead and other heavy metals levels in placenta. We aimed to investigate concentrations of heavy metals, including lead (Pb), cadmium (Cd), chromium (Cr), and nickel (Ni) in placenta from Guiyu and compared them with those from a control area where no e-waste processing occurs. Two hundred and twenty human placentas were collected from Guiyu (n=101) and the control area (n=119). The placenta concentrations of Pb, Cd, Cr, and Ni (PCPb, PCCd, PCCr, and PCNi) were determined by graphite furnace atomic absorption spectrometry (GFAAS). Risk factors of high exposure and correlation with adverse pregnancy outcomes were analyzed using Spearman correlation analyses. PCPb from Guiyu ranged from 6.51 to 3465.16ng/g with a median of 301.43ng/g, whereas PCPb from the control area ranged from 4.53 to 3176.12ng/g with a median of 165.82ng/g (P=0.010). We also observed that in Guiyu, 41.6% of women (42/101) had PCPb>500ng/gwt (wet weight), compared with 24.4% of women (29/119) in the control area (P=0.006). No significant differences of PCCd and PCCr were found between the two groups. In contrast, PCNi was higher in samples from the control area (median 14.30, range 1.76-593.70ng/g) than in Guiyu samples (median 7.64, range 1.19-1108.99ng/g) (P=0.000), and a negative correlation between PCNi and gestational age was found in this study (P=0.017). Spearman correlation analyses showed that there was correlation between PCPb and residence in e-waste recycling area. Environmental pollution, resulted from unregulated e-waste recycling activities, may contribute to elevated PCPb in neonates born in Guiyu and threaten their health.
