ABSTRACT
RATIONALE: Metachronous sternal metastasis of thyroid carcinoma was a rare disease. There was no consensus in the treatment for bone metastasis after the initial thyroid carcinoma surgery. PATIENT CONCERNS: A 53-year-old female patient was hospitalized due to recurrent dull chest pains, with a history of radical right side thyroid carcinoma 4 years ago. On examination, there was an irregular mass on the lower left half of the sternum. Computerized tomography scan showed sternal bone destruction with a soft tissue mass. DIAGNOSES: Metachronous sternal metastasis of thyroid carcinoma. INTERVENTIONS: Partial resection of the sternum and reconstruction with a titanium alloy mesh were performed. OUTCOMES: After a 3-year follow-up, the patient had no recurrence. LESSONS: Surgical resection may be a sufficient treatment for metachronous sternal metastasis of thyroid carcinoma. Biosynthesis material mesh is preferred to be used.
Subject(s)
Bone Neoplasms/surgery , Carcinoma/surgery , Neoplasms, Second Primary/surgery , Plastic Surgery Procedures/methods , Sternum/surgery , Thyroid Neoplasms/surgery , Bone Neoplasms/pathology , Bone Neoplasms/secondary , Carcinoma/pathology , Carcinoma/secondary , Female , Follow-Up Studies , Humans , Middle Aged , Neoplasms, Second Primary/pathology , Plastic Surgery Procedures/instrumentation , Sternum/pathology , Surgical Mesh , Thyroid Neoplasms/pathology , Titanium , Treatment OutcomeABSTRACT
Cryptococcus neoformans is present in areas contaminated with pigeon droppings. Unrecognized infections are hypothesized to occur commonly among immunocompetent individuals. We used serology to estimate prevalence of cryptococcal infection in immunocompetent children from 3 regions. Our results indicate unrecognized cryptococcal infections are extremely common in Bronx children, but uncommon in children from Dutchess County, NY and the Philippines.
