ABSTRACT
1,25(OH) 2 vitamin D 3 is the most effective status of vitamin D in the body.It will play a biological active role when it combines with the receptor of vitamin D. It is common in the chronic kidney disease patients who are lack of vitamin D. The research finds that among the chronic kidney disease patients, in addition to the classic role of vitamin D in regulating calcium and phosphorus metabolism, it can also protect the kidney and delay the progress of chronic kidney disease by blocking the renin-angiotensin system, inhibiting inflammation, reducing podocyte damage and delaying renal fibrosis, etc.This article summarizes the protection mechanism of Vitamin D in the chronic kidney diseases.
ABSTRACT
Objective To study the efficacy and mechanism of probiotic assisted glucocorticoid on the treatment of the patients with eczema. Methods 92 cases with eczema from February 2015 to March 2017 were divided into two groups according to the treatment methods, the conventional group and the combined group, 46 cases in each group. The conventional group were given glucocorticoid, and the combined treatment group were received probiotics combined with glucocorticoid. The levels of serum inflammatory factors, the treatment effects of eczema and the incidence of adverse reactions were compared between the two groups before and after treatment. Results The treatment effect of eczema in combined group was higher than that in routine group (P<0.05). No severe adverse reactions occurred in the two groups. There was no significant difference in serum inflammatory factors between the two groups before treatment. The level of serum inflammatory factors in combined group was significantly better than that in tconventional group (P<0.05). Conclusion Probiotic assisted glucocorticoid is effective in the treatment of eczema. It can lower the level of inflammation and improve the condition of the body. It has no obvious adverse reaction which has the characteristics of safety and effectiveness.
ABSTRACT
Objective To explore influence of thoracic duct ligation on lipid metabolism after esophagectomy. Methods Seventy-four patients with esophageal cancer received esophagectomy were divided into two groups by their thoracic duct ligation, 39 in ligation group and 35 in non-ligation group. All the patients were fed with nutrients through nasal-duodenal tube placed during operation from the 1 st day to the 8th day after surgery, and started taking liquid diet on the 6th day. Blood specimens were collected from the patients on the 1st day after admission, the 9th day, one month and three months after surgery,respectively for biochemical analysis,including determinations of total cholesterol(TC),triglyeeride(TG),high-density lipoprotein-cholesterol ( HDL-C) and low-density lipoprotein-cholesterol ( LDL-C) . Databetween the two groups were compared with statistical analysis. Results No significant difference in plasma levels of TC, TG and HDI.-C was found between the two groups at varied time points. Plasma level of LDL-C in the ligation group significantly decreased on the 9th day after surgery, as compared with that in the nonligation group ( P ＜ 0. 05), and went down to the lowest level one month after surgery. Conclusions Chylomicron was blocked to enter blood stream and production of LDL-C decreased by thoracic duct ligation,which affect lipid absorption and metabolism leading to poor early nutrition in patients with esophagealsurgery due to slower establishment of collateral circulation.
