[Effect of acute cardiac ischemia on the activity of the protein synthesizing system of the internal membranes of myocardial mitochondria]. / Deistvie ostroi ishemii serdtsa na aktivnost' beloksinteziruiushchei sistemy vnutrennikh membran mitokhondrii miokarda.

The effect of acute experimental heart ischemia on protein synthesis and RNA of the internal membranes of myocardial mitochondria was studied; there was a sharp increase in the protein synthesizing system activity of the internal mitochondrial membranes. The most pronounced protein and PNA exchange was noted on the 7th day of the infarction; apparently it was the most critical time in the development of the given pathological process. A study of ultrastructure of mitochondrial membranes in the course of experimental infarction development demonstrated marked changes in their ultrastructure depending on the severity of the disease.

[Effect of disseminated necrotic heart lesions on incorporation of radioactive precursors into the RNA of the inner membranes of rat myocardial mitochondria]. / Vliianie disseminirovannogo nekroticheskogo porazheniia serdtsa na vkliuchenie radioaktivnykh predshestvennikov v RNK vnutrennikh membran mitokhondrii miokarda krys.

The authors studied the role played by the internal membranes of the myocardial mitochondria of rats as the site of radioactive precursors incorporation into the mitochondrial RNA. As revealed, kinetics of the changes of the specific RNA activity of the internal membranes of the myocardial mitochondrial in vivo and in vitro differed. Necrosis of the myocardium induced both in vivo and in vitro significant changes in the specific activity of the RNA of the mitochondrial membranes.