[Application of cell sheet technology in bone and cartilage tissue engineering].

Objective: To review the progress of cell sheet technology and its application in bone and cartilage engineering. Methods: The recent literature concerning the cell sheet technology used in treatment of bone and cartilage defects was extensively reviewed and summarized. Results: Cell sheet built through many different ways can protect extracellular matrix from proteolytic enzymes. As a three-dimensional structure, cell sheet can repair bone and cartilige defects via folding, wrapping scaffold, or be created by the layering of individual cell sheets. Conclusion: The cell sheet technology would have a very broad prospects in bone and cartilage tissue engineering in future.