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1.
Heliyon ; 9(3): e14540, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36950639

ABSTRACT

Video lectures are becoming an important and accessible way for adults to learn a new second language (L2). Unlike face-to-face classroom teaching, teachers are more challenged by the asynchronous mode of video teaching. Finding more effective teaching methods is a great concern for teachers. The present study examined adults' second language (L2) vocabulary learning in a video-based social learning environment. Participants included 116 Chinese undergraduates. They learned German words through one of three pedagogical video lecture conditions: social-context (SC) condition, picture-phonics (PP) condition, and non-picture phonics (NPP) condition. We measured learners' learning performance, cognitive load, intrinsic motivation, and learning satisfaction. The results indicated that adult learners in the SC condition performed significantly better in word meaning retention, had significantly higher intrinsic motivation, and perceived significantly lower cognitive load as compared to the PP and NPP conditions. The implications are that teachers could use social learning pedagogy to create a better video-based learning environment for L2 adult learners for better learning performance.

2.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-426883

ABSTRACT

ObjectiveTo evaluate the therapeutical effect and toxicity of home-made paclitaxel and cisplatin combination in metastatic breast cancer.Methods Home-made paclitaxel 175 mg/m2,d1 intravenous drip,cisplatin 80 mg/m2,d1-3 intravenous drip,21-28 d was one cycle,all patients continuous course treatment for 2-6 cycles,then the effect was evaluated.ResultsAll the patients received meso-cycle were 4 (2-6) cycles chemotherapy.The total effective rate was 56.60% (30/53),disease control rate was 81.13%(43/53 ).The rates of internal organ metastasis and non-internal organ metastasis,before menopause and after menopause had no significant difference [56.76% (21/37) vs.56.25% (9/16),59.09% (13/22) vs.54.84% ( 17/31 ),P > 0.05 ].The median existence time for all the patients was 18.8 ( 12-27 ) months.The survival rate was 56.60% (30/53) and 30.19% (16/53) for 1 and 2 years respectively.The major toxieities were gastrointestinal reaction,alopeoia and myelosuppression,the rates of nerve and heart toxicities were less,15.09% (8/53) and 7.55% (4/53) respectively.ConclusionThe therapeutic effect of home-made paclitaxel and cisplatin combination in metastatic breast cancer is good,it is to be worth to spread in clinic.

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