ABSTRACT
This paper deals with antitumor properties of a fenugreek (Trigonella Foenum Graecum L.) as to the different genesis tumors--the Ca755 mouse mammary carcinoma and the Guerin's carcinoma in rats. Fenugreek powder was shown to inhibit (25-40 %) growth of certain tumors, decrease (27-63%) level of malone dialdehyde in liver, heart and kidney. Consumption of fenugreek was accompanied with decreased polyamines (spermine, spermidine, putrescine) content in tumor tissue. Inclusion of fenugreek to allowance was shown to improve certain blood value.
Subject(s)
Antineoplastic Agents, Phytogenic/therapeutic use , Carcinoma/drug therapy , Mammary Neoplasms, Experimental/drug therapy , Phytotherapy , Plant Preparations/therapeutic use , Powders/therapeutic use , Trigonella/chemistry , Animals , Antineoplastic Agents, Phytogenic/pharmacology , Carcinoma/metabolism , Cisplatin/administration & dosage , Doxorubicin/administration & dosage , Drug Resistance, Neoplasm/drug effects , Female , Heart/drug effects , Kidney/drug effects , Kidney/metabolism , Liver/drug effects , Liver/metabolism , Malondialdehyde/metabolism , Mammary Neoplasms, Experimental/metabolism , Mice , Plant Extracts/administration & dosage , Plant Preparations/pharmacology , Powders/pharmacology , Putrescine/antagonists & inhibitors , Rats , Spermidine/antagonists & inhibitors , Spermine/antagonists & inhibitors , Tumor Burden/drug effectsABSTRACT
A method of phalloscintigraphy, based on the gamma camera and computerized data processing, is offered. The results of examination of patients are described.
Subject(s)
Impotence, Vasculogenic/diagnosis , Penis/blood supply , Penis/diagnostic imaging , Radionuclide Imaging/methods , Computing Methodologies , Gamma Cameras , Humans , Impotence, Vasculogenic/diagnostic imaging , Male , Penis/drug effects , Penis/physiopathology , Piperazines/therapeutic use , Purines , Sildenafil Citrate , Sulfones , Technetium/administration & dosage , Technetium/blood , Vasodilator Agents/therapeutic useABSTRACT
Twenty four hour blood pressure and ECG monitoring, assessment of sexual function (questionnaires, penile artery Doppler flowmetry) were carried out in male hypertensives treated with atenolol, metoprolol, or bisoprolol. Compared with atenolol and metoprolol bisoprolol was found to be more effective and safe. The use of bisoprolol was associated with no negative changes and even with improvement of some parameters of sexual function. Sildenafil could be used for correction of male sexual dysfunction occurring during treatment with other beta-blockers.
