ABSTRACT
OBJECTIVE: Despite the link between positive coronary remodelling and acute ischaemic events, no data exist about the impact of arterial remodelling on subsequent progression of coronary atherosclerosis. The objective of this study was to examine whether extent and direction of arterial remodelling are predictors of progression of coronary atherosclerosis. DESIGN, SETTING AND PATIENTS: From the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial, 210 focal coronary lesions (single lesion per patient) were identified with Subject(s)
Coronary Artery Disease/diagnostic imaging
, Coronary Vessels/diagnostic imaging
, Ultrasonography, Interventional/methods
, Adult
, Aged
, Cholesterol, LDL/drug effects
, Cholesterol, LDL/metabolism
, Coronary Angiography/methods
, Coronary Artery Disease/drug therapy
, Coronary Artery Disease/physiopathology
, Disease Progression
, Female
, Follow-Up Studies
, Humans
, Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
, Male
, Middle Aged
, Predictive Value of Tests
, Randomized Controlled Trials as Topic
, Treatment Outcome
