ABSTRACT
AIM: Determine qualitative and quantitative parameters of mouth and intestines microbiocenosis of healthy people in the age aspect to assess the status of the digestive tract microbiota, as an indicator of human health. MATERIALS AND METHODS: We examined 74 healthy subjects aged 12-18 years who have a comparative aspect investigated qualitative and quantitative composition of the oral fluid and feces microflora. RESULTS: The mouth and intestines microbiota of healthy people has a number of interrelated characteristics defined microbiota of the entire digestive tract The first time were described three variants of the mouth and intestines microbiota, characterized by a certain combination of obligate and facultasive microflora, depending on the age and livelihoods. CONCLUSION: Definition ofmouth and intestines microbiocenosis can be used to assess the status of the digestive tract microbiora as an indicator of health and correction of outlined features through a rational manner of life, balanced diet, pre-and probiorics administration.
Subject(s)
Gastrointestinal Microbiome , Mouth/microbiology , Adolescent , Child , Female , Humans , MaleABSTRACT
The article presents qualitative and quantitative parameters of microbiocenosis of oral fluid and feces of clinically healthy children in different age groups. In most of the cases compensated disbiotic changes were found, which were characterized by reduction in the number of indigenous microflora (lactobacilli and bifidobacteria) and increase of representatives of opportunistic pathogens (Staphylococcus, Bacillus and Candida). Microecological changes in different gastrointestinal biotopes are closely interrelated. Saliva may be considered as a specimen of integral fluid of human environment and can be used for complex assessment of the state of gastrointestinal tract microflora.
Subject(s)
Gastrointestinal Tract/microbiology , Saliva/microbiology , Bacillus/isolation & purification , Bifidobacterium/isolation & purification , Candida/isolation & purification , Child , Child, Preschool , Feces/microbiology , Female , Humans , Lactobacillus/isolation & purification , Male , Monitoring, Physiologic , Staphylococcus/isolation & purificationABSTRACT
To evaluate the efficiency of iodcasein in prophylaxis of iodine-deficient states in servicemen the following parameters were studied: iodine sufficiency determined by ioduria median; thyroid volume measured on the base of US data; functional state of hypothalamo-pituitary-thyroid system evaluated by blood level of thyroid hormone and free thyroxin; physical performance assessed by veloergometric test, auto-and-verbal memory and attention change-over. Iodine deficiency was initially detected in 88.9% (main group) and in 94.4% (control group). Ioduria median corresponded to iodine deficit of middle severity in both groups. After the initial examination the persons from the main group were given iodized bread during 9 months. The monitoring results have confirmed the efficiency of iodine prophylaxis with the use iodcasein.
