ABSTRACT
The complete mitochondrial genome (mitogenome) of Aglossa dimidiata (Lepidoptera: Pyralidae) was sequenced using high-throughput sequencing. The mitogenome of A. dimidiata was 15,225 bp in length. It comprised 37 typical genes and one control region. All protein-coding genes (PCGs) were initiated with ATN, except for COX1 (TTG). All PCGs used TAN as stop codon, except for ND5 and ND4 terminated with incomplete T. Twenty-two tRNA genes ranged from 61 to 71 bp in size. The monophyly of family Pyralidae and the sister relationship between A. dimidiata and Orthopygia glanucinalis are both supported by maximum likelihood method using the nucleotide sequences of 13 PCGs.
ABSTRACT
The complete mitochondrial genome of Cofana yasumatsui (Hemiptera: Cicadellidae: Cicadellinae) is sequenced. Based on annotation, the mitochondrial genome is 15,019 bp, has an A + T content of 77.2% (A = 42.0%, T = 35.2%, G = 10.0%, C = 12.8%), which is the classical structure for insect mitogenome. All PCGs started with ATN, except ATP8 and ND5 starting with TTG. All PCGs used TAN as stop codon, except ND5 stopping with single T. The phylogenetic relationship of C. yasumatsui clustered together with Cicadella viridis, Homalodisca coagulata, Homalodisca vitripennis, and Bothrogonia ferruginea from Cicadellinae. This is identical with the result of the traditional taxonomy.
ABSTRACT
OBJECTIVE: To investigate the value of platelet count in evaluating the degree of liver fibrosis in patients with chronic hepatitis B (CHB). METHODS: A total of 158 CHB patients who underwent liver biopsy in our hospital were included, and the clinical characteristics of these patients were retrospectively analyzed. The diagnostic values of platelet count, aspartate aminotransferase-to-platelet ratio index (APRI), and the fibrosis index based on four factors (FIB-4) for significant fibrosis (F ≥ 2) and early cirrhosis (F = 4) stages in CHB patients were assessed by the use of receiver operating characteristic (ROC) analysis. RESULTS: The median (F0: 221.0; F1: 210.0; F2: 188.0; F3: 171.0; and F4: 155.5) and mean rank (F0: 120.4; F1: 100.1; F2: 82.2; F3: 67.9; and F4: 49.5) of platelet count decreased along the aggravation of fibrosis (F0-F4). The areas under the ROC curve for the platelet count in diagnosis of significant fibrosis stage was 0.70, which had no significant difference with FIB-4 (0.73) and APRI (0.68) in diagnostic efficacy (P = .428). The areas under the ROC curve of platelet count in diagnosis of early cirrhosis were 0.72, which had no significant difference with FIB-4 (0.76) and APRI (0.68) (P = .094). CONCLUSION: The platelet count, as a simple and non-invasive index, could evaluate the degree of liver fibrosis in CHB individuals. At the same time, the diagnostic efficiency of platelet count to evaluate the significant liver fibrosis and early cirrhosis is comparable to FIB-4 and APRI.
Subject(s)
Hepatitis B, Chronic/blood , Hepatitis B, Chronic/pathology , Liver Cirrhosis/pathology , Platelet Count , Adult , Aspartate Aminotransferases/blood , Female , Humans , Liver Cirrhosis/blood , Liver Cirrhosis/virology , Male , Middle Aged , ROC Curve , Retrospective StudiesABSTRACT
We determined the complete mitochondrial genomes of Crenidorsum turpiniae, a new record whitefly pest on tea-tree. The mitogenome of C. turpiniae is 15,427 bp long and consists of 13 protein-coding genes, 22 tRNA genes, two rRNA genes and a putative control region (GenBank: MN934936). The whole base composition of the heavy strand for A, C, G and T is 30%, 12.24%, 15.82% and 41.87%, respectively, with an AT bias (-16%). All PCGs use ATN as start codon (N, any nucleotide), except for NAD6 uses TTG. Most of the PCGs use TAA as a stop codon. The length of 16SrRNA and 12SrRNA gene are 1277 bp and 768 bp, respectively. Phylogenetic analysis indicated that C. turpiniae and Tetraleurodes acaciae had a closer genetic relationship.
