ABSTRACT
Objective To explore the effectiveness and safety of tiotropium bromide inhalation agent with tulobuterol patch in the treatment of C and D level of COPD in stable period .Methods According to the digital table,255 cases of C and D level in patients with stable COPD were randomly divided into the study group and control group,the patients in study group received inhalation of tiotropium bromide dry powder 18μg/times,one time every day,and give tulobuterol patch(2mg/paste),one time every day.The control group received inhalation of tiotropium bromide dry powder 18μg/times,one time every day.The changes of lung function were observed before and after treatment,the clinical symptom score and inhaled short acting beta 2 agonists used,6min walk test,times of acute exacerbation condition.Results The patients in the two groups after treatment ,pulmonary function ,clinical symptoms score,inhaled short acting beta 2 agonists used,6min walk test,times of acute exacerbation compared with statistical significance(all P0.05).Conclusion Tiotropium bromide inhalation agent with tulobuterol patch can improve clinical symptoms and pulmonary function in patients with C and D level part of the stable phase of COPD .
ABSTRACT
OBJECTIVE: To investigate the value about GINA escalation therapy of bronchial asthma. METHODS: 64 asthma patients in investigation group were divided into several grades according to the severity degree and escalation therapy was carried out according to GINA. 62 asthma patients in control group were treated by routine method. The medical cost and clinical symptom of asthma were studied. RESULT: The attack times, the days of cough and gasping, the times of hospitalization, FEV1 and PEF after treatment for 3 years were lower than those before treatment (P < 0.01). The above-mentioned markers in the investigation group were lower than those in the control group (P < 0.05). The medical cost in the investigation group was lower than that in the control group (P < 0.05). CONCLUSION: The effect of GINA project on preventing and curing asthma is better than that of routine method. The GINA project plays an important role in improving the quality of life and decreasing the medical cost.
