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1.
Ter Arkh ; 75(1): 59-62, 2003.
Article in Russian | MEDLINE | ID: mdl-12652960

ABSTRACT

AIM: To determine the significance of the damage index (SLICC/ACR DI) in the prognosis of the outcome of systemic lupus erythematosus (SLE). MATERIALS AND METHODS: Correlations between the disease activity, cumulative damage and outcome were studied in 103 patients with SLE divided into two groups by the disease duration (21 to 60 months--group 1, 62 to 488 months--group 2). SLE activity was determined by Nasonova's classification, SLEDAI-1 and ECLAM. Cumulative damage was assessed by the damage index (systemic lupus international collaborating clinics/ACR damage index). RESULTS: We found the direct correlation between the age of the disease onset, SLE duration, degree of SLE activity and the damage index and between the maximal dose of glucocorticosteroids and the damage index. CONCLUSION: The results indicate that SLICC/ACR DI may be useful for outcome prediction in SLE.


Subject(s)
Lupus Erythematosus, Systemic/physiopathology , Adolescent , Adult , Case-Control Studies , Female , Humans , Male , Middle Aged , Prognosis
2.
Klin Med (Mosk) ; 80(4): 62-4, 2002.
Article in Russian | MEDLINE | ID: mdl-12043269

ABSTRACT

A case of systemic lupus erythematosus with deforming hand arthropathy (DHA) is reported in a woman observed for 15 years. DHA was presented with stable ulnar deviation, deformation of the fingers. This resulted in functional insufficiency of the hand of the third degree.


Subject(s)
Arthropathy, Neurogenic/complications , Arthropathy, Neurogenic/physiopathology , Hand/physiopathology , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/physiopathology , Adult , Female , Humans
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