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1.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 30(2): 229-33, 2013 Apr.
Article in Chinese | MEDLINE | ID: mdl-23858738

ABSTRACT

In this research, we compared the visual neuron responses for LGN, A18 and PMLS of old and young cats with extracellular single-neuron recording techniques. We used firing rate vector to characterize information, and response irregularity of cells to evaluate the degeneration of visual characters. Response irregularity is characterized by means of the two coefficients of variation of firing rate vectors: Cv and Cv2. We found that there was no significant change of the response irregularity in LGN areas during the aging process from young to old cats. But in the other two areas, neurons of old cats exhibited significantly larger response irregularity than those of young cats. The result indicated that the information processing function of advanced visual cortex was impaired by aging. This result also provids a reference for the research of the other neuronal system changes during aging process.


Subject(s)
Action Potentials/physiology , Aging/physiology , Neurons/physiology , Visual Cortex/physiology , Animals , Cats , Neural Conduction
2.
Dongwuxue Yanjiu ; 33(5): 498-502, 2012 Oct.
Article in Chinese | MEDLINE | ID: mdl-23019032

ABSTRACT

The middle temporal area (MT/V5) plays an important role in motion processing. Neurons in this area have a strongly selective response to the moving direction of objects and as such, the selectivity of MT neurons was proposed to be a neural mechanism for the perception of motion. Our previous studies have found degradation in direction selectivity of MT neurons in old monkeys, but this direction selectivity was calculated during the whole response time and the results were not able to uncover the mechanism of motion perception over a time course. Furthermore, experiments have found that direction selectivity was enhanced by attention at a later stage. Therefore, the response should be excluded in experiments with anesthesia. To further characterize the neural mechanism over a time course, we investigated the age-related changes of direction selectivity in the early stage by comparing the proportions of direction selective MT cells in old and young macaque monkeys using in vivo single-cell recording techniques. Our results show that the proportion of early-stage-direction-selective cells is lower in old monkeys than in young monkeys, and that the early stage direction bias (esDB) of old MT cells decreased relative to young MT cells. Furthermore, the proportion of MT cells having strong early stage direction selectivity in old monkeys was decreased. Accordingly, the functional degradation in the early stage of MT cells may mediate perceptual declines of old primates in visual motion tasks.


Subject(s)
Aging/psychology , Disease Models, Animal , Macaca mulatta/physiology , Motion Perception , Motor Neurons/physiology , Aging/physiology , Animals , Humans , Motion
3.
Zhongguo Yi Liao Qi Xie Za Zhi ; 33(3): 172-5, 2009 Mar.
Article in Chinese | MEDLINE | ID: mdl-19771889

ABSTRACT

Based on the deep analysis of existing fingerprint identification algorithms, this article proposes an integrative solution to adopt the fingerprint identification technology into EMRS Electronic Medical Records System. It may improve the security of EMRS and raise the working efficiency of physicians effectively.


Subject(s)
Dermatoglyphics , Medical Records Systems, Computerized , Algorithms , Humans
4.
Zhongguo Yi Liao Qi Xie Za Zhi ; 33(2): 83-6, 149, 2009 Mar.
Article in Chinese | MEDLINE | ID: mdl-19565789

ABSTRACT

The user experience (EX) of current Electronic Medical Record systems (EMR) is needed to improve. This paper proposed a new method to enhance EX of EMR. Firstly, system template and text characterization are used to make the EMR data structured. Then, the structured date are mined based on mining the association rules of incremental updating data to find the association of the elements of template of EMR and the values of elements. Finally, with the help of mined results, the users of EMR are able to input data effectively and quickly.


Subject(s)
Data Mining/methods , Electronic Health Records , Medical Records Systems, Computerized , Information Systems , User-Computer Interface
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