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1.
BMJ Open ; 12(11): e062407, 2022 11 11.
Article in English | MEDLINE | ID: mdl-36368758

ABSTRACT

OBJECTIVES: Women with breast cancer have different needs that are various in perceived importance and satisfaction. This study aimed to examine the relationship among perceived needs satisfaction, perceived needs importance with health-related quality of life (HRQoL) in women with breast cancer and determine the intermediary role of perceived needs importance in the relationship between perceived needs satisfaction and HRQoL. DESIGN: Cross-sectional design. SETTING: Two tertiary level hospitals in Shaanxi Province, China. PARTICIPANTS: Women newly diagnosed with breast cancer were recruited. OUTCOME MEASURES: The Needs Self-Rating Questionnaire for Breast Cancer and the Medical Outcomes Study 36-item Short-Form Health Survey V. 2.0 were used for data collection regarding perceived needs satisfaction, perceived needs importance and HRQoL. RESULTS: A total of 359 valid questionnaires were collected. The perceived needs importance was negatively associated with physical component summary (PCS) (b=-0.067, p=0.024) and mental component summary (MCS) (b=-0.185, p<0.001). On the contrary, perceived needs satisfaction was positively associated with PCS (c'=0.005, p=0.843), although not statistically significant. Perceived needs satisfaction was positively associated with MCS (c'=0.194, p<0.001) and perceived needs importance (a=0.458, p<0.001). Furthermore, the perceived needs importance suppressed the relationship between perceived needs satisfaction and PCS (a*b=-0.031; 95% CI -0.058 to -0.004) and the relationship between perceived needs satisfaction and MCS (a*b=-0.085; 95% CI -0.138 to -0.043). CONCLUSION: For women with breast cancer, higher perceived needs satisfaction is associated with higher HRQoL. However, higher perceived needs importance would be conversely associated with lower HRQoL by suppressing the positive association of perceived needs satisfaction with HRQoL. Healthcare providers should pay more attention to those who have high perceived needs importance but low perceived needs satisfaction and fulfil the important needs.


Subject(s)
Breast Neoplasms , Quality of Life , Female , Humans , Cross-Sectional Studies , Breast Neoplasms/drug therapy , Surveys and Questionnaires , Health Surveys
2.
BMC Womens Health ; 22(1): 198, 2022 05 28.
Article in English | MEDLINE | ID: mdl-35643446

ABSTRACT

BACKGROUND: Breast cancer may impair health-related quality of life (HRQoL). We examined the mediating roles of perceived social support (PSS) and coping style (CS) in the relationship between resilience and HRQoL in newly diagnosed breast cancer patients. METHODS: Following a cross-sectional design, 431 patients completed a survey at two hospitals in Shaanxi Province, China. Four validated self-report measures assessed HRQoL, psychological resilience, PSS, and CS. A one-sample t-test analyzed differences between resilience, PSS, and CS in breast cancer patients and the corresponding norm. Multivariate linear regression analyzed the independent predictors of HRQoL. The mediating roles of PSS and CS between resilience and HRQoL were investigated using structural equation modeling (SEM). RESULTS: Participants had significantly lower scores for resilience and PSS, and higher scores for the avoidance and resignation CSs than their corresponding norm. SEM analysis showed resilience had significant direct effects on PSS (Bs: 0.59, 95% CI 0.49, 0.68, P = 0.003), CS (confrontation: 0.53 (0.44, 0.62), P = 0.001; resignation: - 0.66 (- 0.74, - 0.57), P = 0.002), and HRQoL (Bs range from 0.44 to 0.63, P < 0.05). Resilience had significant indirect effects (Bs range from 0.09 to 0.27), and PSS and CS had significant direct effects on HRQoL (P < 0.05). CONCLUSIONS: Newly diagnosed breast cancer patients had lower resilience and PSS, and higher negative CSs, suggesting that PSS and CS mediated the influence of resilience on HRQoL. A multimodal intervention program focusing on PSS and CS might improve the positive influences of resilience on HRQoL in breast cancer patients.


Subject(s)
Breast Neoplasms , Quality of Life , Adaptation, Psychological , Breast Neoplasms/psychology , Cross-Sectional Studies , Female , Humans , Quality of Life/psychology , Social Support
3.
BMC Womens Health ; 22(1): 61, 2022 03 04.
Article in English | MEDLINE | ID: mdl-35246115

ABSTRACT

BACKGROUND: Breast cancer survivors experience altered body image and quality of life (QoL) due to the disease and its treatment. The multidimensional nature of body image and QoL makes their relationships complex. This study aimed to examine the associations between the two concepts in Chinese breast cancer survivors and test whether these associations are moderated by rural-urban residence. METHODS: A cross-sectional design was adopted. Breast cancer survivors were recruited via a convenience sampling method. Two validated questionnaires (the Body Image Self-Rating Questionnaire for Breast Cancer and 36-item Short-Form Health Survey) and questions assessing demographic and clinical covariates were administered. Multiple linear regressions were used to assess the relationship between body image and QoL domains and to examine the moderating effect of rural-urban residence. RESULTS: In our sample of 354 breast cancer survivors, half (50.28%) lived in rural areas. After adjusting for demographic and clinical variables, better perception of body image-related sexual activity change, role change, and psychological change was significantly associated with better physical (ß ranged from - 0.15 to - 0.11, p < 0.05) and mental (ß ranged from - 0.46 to - 0.34, p < 0.001) well-being. Better perception of body image-related social and behavior change was significantly associated only with better mental well-being (ß ranged from - 0.40 to - 0.33, p < 0.001). The association between body image and mental well-being was much stronger in urban subjects (b = - 0.38, p < 0.001) than in rural subjects (b = - 0.20, p < 0.001). CONCLUSIONS: Our findings suggest that multidimensional body image is associated with physical and mental well-being in Chinese breast cancer survivors. Body image appears to play a larger role in urban breast cancer survivors' mental well-being. Our results indicate that incorporating interventions that address body image issues would be advantageous for survivorship care to enhance QoL in breast cancer survivors. Furthermore, rural-urban differences should be considered in the strategic design of survivorship care programs in rural and urban settings.


Subject(s)
Breast Neoplasms , Cancer Survivors , Body Image , Breast Neoplasms/psychology , Cancer Survivors/psychology , China , Cross-Sectional Studies , Female , Humans , Quality of Life/psychology , Surveys and Questionnaires
4.
BMC Cancer ; 22(1): 57, 2022 Jan 12.
Article in English | MEDLINE | ID: mdl-35022019

ABSTRACT

BACKGROUND: Although many psychological factors have been associated with health-related quality of life (HRQoL), the mediator role of resilience between psychological predictors (i.e., coping styles and perceived social support) and HRQoL has rarely been explored in breast cancer survivors (BCSs). METHODS: A total of 231 BCSs participated in this cross-sectional survey. Pearson correlation was performed to analyze the relationships among coping styles (confrontation, avoidance, and resignation), perceived social support, resilience, and HRQoL. A multivariate linear regression analysis was applied to identify the psychological predictors of HRQoL and resilience, respectively. A structural equation modeling (SEM) was employed to examine the mediating role of resilience between coping styles, perceived social support, and HRQoL. RESULTS: Perceived social support and resilience were positively associated with confrontation. Resilience was positively associated with perceived social support. HRQoL had positive correlations with confrontation/avoidance, perceived social support, and resilience. Resilience and resignation/avoidance were significant independent predictors of HRQoL, while resignation/confrontation and perceived social support were significant independent predictors of resilience. Confrontation/resignation, perceived social support, and resilience had significant direct effects on HRQoL; confrontation/resignation and perceived social support had significant direct effects on resilience; resilience had significant mediator roles between confrontation/resignation, perceived social support, and HRQoL. CONCLUSIONS: Resilience was a significant mediator between coping styles, perceived social support, and HRQoL. A resilience-oriented intervention is recommended to alleviate the detrimental influences of low resilience on HRQoL, providing a new strategy for improving the health status of BCSs.


Subject(s)
Breast Neoplasms/psychology , Cancer Survivors/psychology , Cancer Survivors/statistics & numerical data , Quality of Life/psychology , Resilience, Psychological/physiology , Adult , Cross-Sectional Studies , Female , Humans , Middle Aged , Social Support
5.
Int J Ment Health Syst ; 15(1): 11, 2021 Jan 19.
Article in English | MEDLINE | ID: mdl-33468192

ABSTRACT

BACKGROUND: In many low resource settings, the provision of government mental health care services is limited to specialized psychiatry units in urban hospital care facilities, where the most common treatment for common mental disorders (CMDs) is pharmacotherapy, occasionally with adjunct nonspecific psychological support. We aimed to evaluate the effectiveness of adding a low intensity, psychological intervention, Problem Management Plus (PM+) for CMDs into routine care in a specialized mental health care facility in Pakistan. METHODS: A two arm, single-blind individual randomized controlled trial (RCT) was carried out with adults (N = 192), referred for psychological support by psychiatrists. The study participants were randomized (1:1) to PM + plus Treatment as Usual (TAU) (n = 96) or TAU only (n = 96). The primary outcomes were symptoms of anxiety and depression, measured by the Hospital Anxiety and Depression Scale (HADS) and functional impairment as measured by WHO Disability Assessment Schedule (WHODAS 2.0) at 20 weeks after baseline. RESULTS: The analysis was done on intention-to-treat principle. The linear mixed model analysis showed that at 20 weeks after baseline, there was a significant reduction in symptoms of anxiety and depression (mean [SD], 16.23 [8.81] vs 19.79 [7.77]; AMD, - 3.10; 95% CI, - 0.26 to - 5.76); p = 0.03 and improvement in functioning (mean [SD], 22.94 [9.37] vs 27.37 [8.36]; AMD, - 4.35; 95% CI, - 1.45 to - 7.24); p = 0.004 in PM + plus TAU versus TAU arm. The follow-up rate was 67% at primary end-point. CONCLUSIONS: Specialized care facilities in LMICs may consider adding brief, evidence-based psychological treatments for CMDs to their routine care. Trial Registration Australian New Zealand Clinical Trials Registry, ACTRN12616000381482. Registered March 23, 2016. Retrospectively registered, https://www.anzctr.org.au/Default.aspx/ ACTRN12616000381482.

6.
Health Qual Life Outcomes ; 18(1): 163, 2020 Jun 01.
Article in English | MEDLINE | ID: mdl-32487117

ABSTRACT

BACKGROUND: Although body image (BI) disturbance is a common problem that often contributes to poor health-related quality of life (HRQoL) among women with breast cancer following surgery, the mediating role of BI (as a self-perceptive factor) in the relationship between needs and HRQoL after controlling for socio-demographic factors remains unclear. The purpose of this study was to identify the mediating role of BI between post-surgery needs and HRQoL after controlling for socio-demographic factors among women with breast cancer. METHODS: In this cross-sectional study, the primary outcome was HRQoL (as measured with the 36-item Short-Form Health Survey version 2 [SF-36v2] and Functional Assessment of Cancer Therapy-Breast version 4.0 [FACT-Bv4.0]). The secondary outcomes included needs (measured in terms of needs importance [NI] and needs satisfaction [NS]) and BI. Structural equation modeling was used to identify the mediating role of BI between needs and HRQoL while considering socio-demographics. RESULTS: The 406 eligible patients reported poor HRQoL, and approximately half reported important unmet needs and poor BI. NI, NS, and socio-demographics had differing direct effects on BI and HRQoL, and contrasting indirect effects on HRQoL via BI. NI, NS, surgery type, presence of chronic disease, and BI explained 4% of the variance in the SF-36v2 physical component summary score; NI, NS, surgery type, residence, and BI explained 20% of the variance in the mental component summary score; and NI, NS, marital status, employment status, radiotherapy, and BI explained 33% of the variance in the FACT-Bv4.0 total score. CONCLUSIONS: After surgery, women with breast cancer have poor HRQoL and BI, and important unmet needs. BI mediates the relationship between needs and HRQoL after controlling for socio-demographics. The present findings provide information for developing comprehensive BI-based needs interventions and preparing targeted health-management programs for patients with breast cancer.


Subject(s)
Body Image/psychology , Breast Neoplasms/psychology , Quality of Life , Adult , Cross-Sectional Studies , Female , Humans , Middle Aged , Postoperative Period , Surveys and Questionnaires
7.
Int J Nurs Stud ; 106: 103565, 2020 Jun.
Article in English | MEDLINE | ID: mdl-32272281

ABSTRACT

BACKGROUND: Primary treatments for early-stage breast cancer can cause adverse effects, such as pain, fatigue, and sleep disturbance, that can markedly affect the patients' health-related quality of life. OBJECTIVE: This study aimed to evaluate the benefits of a WeChat-based multimodal nursing program on early rehabilitation in postoperative women with breast cancer. DESIGN: Clinical randomized controlled trial. SETTING: Surgical breast cancer department of a general hospital in Shaanxi Province, China. PARTICIPANTS: Women with breast cancer were recruited via convenience sampling. The inclusion criteria were (1) age ≥18 years, (2) newly diagnosed with breast cancer, (3) stage I-III disease, and (4) indicated for surgery with adjuvant therapy. Exclusion criteria were (1) comorbidity with other malignant tumors and infections and (2) cognitive or psychiatric disorders. METHODS: We recruited patients with breast cancer and randomly allocated them to the intervention (n = 56) and control (n = 55) groups. The former was subjected to the WeChat-based multimodal nursing program plus routine nursing care for 6 months, whereas the latter received only routine nursing care. The primary endpoint (health-related quality of life) and secondary endpoints (pain, fatigue, and sleep) were measured using the Functional Assessment of Cancer Therapy-Breast version 4.0 (FACT-Bv4.0) and the Numerical Rating Scale at 4 time points (i.e., pre-surgery and 1, 3, and 6 months post-surgery). RESULTS: The intervention group had significantly improved total FACT-Bv4.0 scores owing to the effects of group (F = 16.28, P < 0.001), time (F = 28.82, P < 0.001), and group-time interaction (F = 5.35, P = 0.001). Similar improvements were also found in social/family well-being and functional well-being (P < 0.05). Emotional well-being was improved based on the effects of time (F = 42.12, P < 0.001) and group-time interaction (F = 10.20, P < 0.001). The 'breast cancer-specific subscale for additional concerns' was affected by group (F = 21.55, P < 0.001) and time (F = 28.96, P < 0.001), whereas physical well-being was only affected by time (F = 35.39, P < 0.001). Pain, fatigue, and sleep were not significantly influenced by group effects. CONCLUSIONS: We found a significant improvement in the health-related quality of life of postoperative women with breast cancer who used the WeChat-based multimodal nursing program during early rehabilitation. This demonstrated that the program is an effective intervention for postoperative rehabilitation in such patients. Findings of the study will provide evidence for eHealth services in clinical and transitional nursing care.


Subject(s)
Breast Neoplasms/psychology , Rehabilitation/instrumentation , Social Media/standards , Adult , Anxiety/psychology , Anxiety/therapy , Breast Neoplasms/therapy , China , Depression/psychology , Depression/therapy , Female , Humans , Mastectomy/methods , Middle Aged , Postoperative Period , Program Development/methods , Rehabilitation/methods , Rehabilitation/standards , Social Media/statistics & numerical data
9.
Breast Cancer Res Treat ; 178(1): 95-103, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31342310

ABSTRACT

PURPOSE: Psychological resilience is an important ability for women with breast cancer to cope effectively with depression and anxiety. However, the demands of long-term hospital-based psychological rehabilitation interventions are not met in mainland China, where shorter hospital stays and longer home rehabilitation are common. This study examines whether a cyclic adjustment training (CAT) intervention delivered via a mobile device can improve psychological resilience, and reduce depression and anxiety symptoms, in a population of post-surgical women with breast cancer. METHODS: Women with breast cancer were recruited through convenience sampling from a general hospital in Xi'an, and randomly allocated to an intervention group (n = 66), receiving CAT plus routine nursing care for 12 weeks, or a control group (n = 66), receiving only routine nursing care. The primary outcome was psychological resilience. Resilience, anxiety, and depression were measured using the Connor-Davidson Resilience Scale (CD-RISC), Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS), respectively. A linear mixed model was applied to analyze the effects. RESULTS: Patients in the CAT group displayed significantly improved psychological resilience, anxiety, and depression scores (F = 19.53, P < 0.001; F = 31.85, P < 0.001; F = 26.32, P < 0.001), respectively, compared to the control group. CONCLUSIONS: The CAT had positive effects on improving psychological resilience and reducing the symptoms of anxiety and depression, supporting its use as an effective psychological management and intervention strategy in the early stages of long-term rehabilitation of post-surgical women with breast cancer. TRIAL REGISTRATION: Chictr.org.cn ChiCTR-IOR-16008253, registered 9 April 2016.


Subject(s)
Anxiety/rehabilitation , Breast Neoplasms/surgery , Depression/rehabilitation , Psychotherapy/instrumentation , Adult , Breast Neoplasms/psychology , Cell Phone , China , Cognitive Behavioral Therapy , Female , Humans , Middle Aged , Quality of Life , Resilience, Psychological , Treatment Outcome
10.
Ann Surg Oncol ; 26(7): 2156-2165, 2019 Jul.
Article in English | MEDLINE | ID: mdl-30972655

ABSTRACT

OBJECTIVE: The aim of this study was to examine the effects of progressive upper limb exercises and muscle relaxation training (PULE-MRT) on upper limb function and health-related quality of life (HRQoL) following surgery in Chinese mainland women with breast cancer (BC). METHODS: Overall, 102 patients following surgery (i.e. mastectomy or breast-conserving surgery, with sentinel lymph node biopsy or axillary lymph node dissection) were randomly allocated to the intervention (n = 51) or control (n = 51) groups. The former received PULE-MRT plus routine nursing care, whereas the latter received only routine nursing care for 6 months. Upper limb function and HRQoL were measured at baseline and 1, 3, and 6 months using Constant-Murley scores (CMS) and Functional Assessment of Cancer Therapy-Breast version 4.0 (FACT-Bv4.0), respectively. RESULTS: All patients in the intervention group completed the exercises and training, with 100% compliance and no adverse events. The intervention group had significantly higher total CMS and FACT-Bv4.0 scores at 1-, 3-, and 6-month follow-up than the control group. The significant effects in total CMS comparisons were group (F = 25.30, p < 0.001), time (F = 18.02, p < 0.001), and group-by-time interaction (F = 9.95, p < 0.001), and, in FACT-Bv4.0, total score comparisons were group (F = 15.87, p < 0.001), time (F = 17.92, p < 0.001), and group-by-time interaction (F = 7.88, p < 0.001). Similar results were observed for the scale scores of CMS and FACT-Bv4.0. CONCLUSIONS: PULE-MRT had positive effects on improving upper limb function and HRQoL following surgery in women with BC and could be used as an optional rehabilitation management strategy in post-surgery BC patient populations. Trial Registration ChiCTR-IOR-16008253 (Chictr.org.cn; 9 April 2016).


Subject(s)
Breast Neoplasms/rehabilitation , Exercise Therapy , Mastectomy/rehabilitation , Muscle Relaxation , Quality of Life , Upper Extremity/innervation , Breast Neoplasms/surgery , Female , Humans , Prognosis , Retrospective Studies
11.
J Eval Clin Pract ; 25(5): 889-895, 2019 Oct.
Article in English | MEDLINE | ID: mdl-30773748

ABSTRACT

RATIONALE, AIMS, AND OBJECTIVES: A needs assessment tool considering the cultural background of mainland China has not been reported. This study developed a Needs Self-rating Questionnaire for Breast Cancer (NSQ-BC) based on Maslow's hierarchy of needs for mainland Chinese patients. METHODS: The Delphi technique and pilot cross-sectional surveys (two rounds) were performed for item selection. In the Delphi technique, items were selected according to the experts' perspective on the item's significance (ie, 1-5 Likert-scale ratings of importance; mean > 4.0 and coefficients of variation <0.25). In the pilot cross-sectional surveys, items were selected according to internal consistency reliability (Cronbach's α ≥ 0.70), discriminant validity (stronger correlations of the item with the hypothesized subscale than for other subscales), and convergent validity (hypothesized item-subscale correlations ≥0.40). All decisions were made based on the results of statistical analyses, recommendations of the experts, and in-depth discussion among research team members. RESULTS: Following the two evaluation rounds, the revised NSQ-BC comprised 26 items across five subscales of needs: physical, psychological, respect/self-esteem, information, and rehabilitation. Item ratings from the expert panellists met the aforementioned criteria (ie, Kendall's W = 0.329, P < 0.001). Except for the "respect/self-esteem needs" subscale, Cronbach's α for all subscales exceeded 0.70. All items had acceptable discriminant and convergent validity. Additionally, two new items-good environment/facilities and economic support-were added to the NSQ-BC, as recommended by the experts. CONCLUSIONS: The NSQ-BC was developed fully via the comprehensive use of Delphi technique and pilot cross-sectional surveys. It provides evidence of a proper instrument for needs assessment and evaluation among women with breast cancer in mainland China.


Subject(s)
Breast Neoplasms , Needs Assessment/statistics & numerical data , Patient Outcome Assessment , Psychometrics , Quality of Life , Breast Neoplasms/epidemiology , Breast Neoplasms/psychology , China/epidemiology , Delphi Technique , Female , Humans , Middle Aged , Psychology , Psychometrics/methods , Psychometrics/standards , Reproducibility of Results , Surveys and Questionnaires
12.
J Eval Clin Pract ; 25(5): 864-872, 2019 Oct.
Article in English | MEDLINE | ID: mdl-30548365

ABSTRACT

RATIONALE, AIMS, AND OBJECTIVES: The psychometrics of the Short-Form 36 Health Survey version 2 (SF-36v2) in female breast cancer patients remains unknown. This study aimed to test the reliability, validity, and sensitivity of the Chinese SF-36v2 in women with breast cancer. METHODS: The sample included 326 eligible participants. The reliability and the item convergent and discriminant validity were estimated using Cronbach α (≥0.70) and the multi-trait multi-item matrix analysis, respectively. The structural validity was tested using confirmatory factor analysis. Sensitivity was determined via an analysis of variance and the relative efficiency for initially diagnosed cases (yes vs no) as well as the time since diagnosis (years) before and after stratifying by initially diagnosed cases. RESULTS: The overall Cronbach α was 0.91 (eight scales range: 0.72-0.92). All hypothesized item-scale correlations were greater than the alternatives (r ≥ 0.40). With acceptable model fit indices, the physical functioning, role-physical, bodily pain, and general health subscales had stronger contributions to the physical component summary (goodness-of-fit index [GFI]: 0.92, parsimony goodness-of-fit index [PGFI]: 0.60, comparative fit index [CFI]: 0.91, Tucker-Lewis index [TLI]: 0.93, adjusted goodness-of-fit index [AGFI]: 0.91, root mean square error of approximation [RMSEA]: 0.06, normed chi-squared [NC]: 2.65), while the vitality, social functioning, role-emotional, and mental health subscales contributed more to the mental component summary (GFI: 0.91, PGFI: 0.62, CFI: 0.91, TLI: 0.92, AGFI: 0.91, RMSEA: 0.07, NC: 2.76). The relative efficiencies with significant F-statistics were found for mental health (relative efficiency: 34.28; initially diagnosed cases), physical functioning (12.88; time since diagnosis), and physical functioning (5.80), role-physical (5.15), bodily pain (7.70), social functioning (4.62), role-emotional (4.72), mental health (4.75), and physical component summary (6.96; initially diagnosed cases with time since diagnosis; P < 0.05 for all variables). CONCLUSIONS: Chinese SF-36v2 has acceptable psychometric properties and is suitable for women with breast cancer.


Subject(s)
Breast Neoplasms/psychology , Psychometrics , Quality of Life , Translations , Adult , Breast Neoplasms/epidemiology , China , Cross-Sectional Studies , Female , Health Surveys/methods , Humans , Middle Aged , Psychometrics/methods , Psychometrics/standards , Reproducibility of Results , Self Concept , Surveys and Questionnaires
13.
BMC Cancer ; 18(1): 19, 2018 01 04.
Article in English | MEDLINE | ID: mdl-29301503

ABSTRACT

BACKGROUND: Body image is a complex post-treatment concern among female patients with breast cancer, and various tools have been developed and applied to measure this multifaceted issue. However, these available tools were developed in other countries and only a few have been modified into Chinese versions. Furthermore, body-image evaluation instruments that are specific to Chinese mainland female patients with breast cancer have not been devised yet. Therefore, we developed the Body Image Self-rating Questionnaire for Breast Cancer for Chinese mainland female patients with breast cancer. METHODS: We performed two rounds of the Delphi technique and a cross-sectional pilot survey. Items were selected using a Likert scale (1-5) to determine ratings of importance (i.e., the significance of the item from experts' perspective; coefficients of variation ≤0.25), internal consistency reliability (Cronbach's α ≥ 0.70), convergent validity (hypothesized item-subscale correlations ≥0.40), and discriminant validity (stronger correlations of the item with the hypothesized subscale than for other subscales). All decisions on items were made based on statistical analysis results, experts' recommendations, and in-depth discussion among researchers. RESULTS: Twenty-five eligible experts completed the two Delphi rounds (mean age: 42.20 ± 8.90 years). Over half the experts were professors (56%, n = 14) or worked as clinical staff (68%, n = 17). Twenty (mean age = 49.55 ± 10.01 years) and 50 patients (mean age = 48.44 ± 9.98 years) completed the first- and second-round survey, respectively. Over half the patients had a tertiary education level, were married, and were employed. Regarding the revised questionnaire (comprising 33 items across seven subscales), the expert panelists' ratings of each item met the criteria (Kendall's W = 0.238, p < .001). Five subscales had a Cronbach's α value over 0.60 (range: 0.62-0.69) and two subscales were over 0.80 (range: 0.84-0.88). All items satisfied the criteria for convergent and discriminant validity. CONCLUSIONS: The findings of this study provide evidence of a suitable tool for body image evaluation among Chinese mainland female patients with breast cancer. Studies with larger sample sizes should be conducted to validate this questionnaire in this patient population.


Subject(s)
Body Image , Breast Neoplasms/diagnostic imaging , Breast Neoplasms/epidemiology , Adult , Aged , Breast Neoplasms/therapy , China/epidemiology , Delphi Technique , Female , Humans , Male , Middle Aged , Psychometrics , Quality of Life , Surveys and Questionnaires
14.
PLoS One ; 12(6): e0179009, 2017.
Article in English | MEDLINE | ID: mdl-28586356

ABSTRACT

This study aimed to explore the bidirectional relationships between retention and health-related quality of life (HRQoL) in patients from mainland China receiving methadone maintenance treatment (MMT). This prospective cohort study recruited 1,212 eligible MMT patients from the two largest MMT clinics (one privately and another publicly funded) in Xi'an. This study started in March 2012 with a 2-year follow-up until March 2014. Retention was assessed by repeated terminations, past treatment duration, premature terminations, and follow-up treatment duration. HRQoL was evaluated using the Chinese (simple) short-form 36 health survey version 2 (SF-36v2) and the quality of life scale for drug addicts (QOL-DAv2.0). Linear and Cox regression analyses were used to explore relationships between retention and HRQoL. A general linear model was used to further examine the global effect of past treatment duration on HRQoL. Multivariate analyses showed that repeated terminations had no significant impact on HRQoL scores in MMT patients; however, past treatment time (year) influenced the SF-36v2PCS (P = 0.004): treatment for ≥4 years showed a lower SF-36v2PCS score (regression coefficient: -2.39; 95% confidence interval [CI]: -3.80, -0.97; P = 0.001) than treatment for <1 year. In addition, patients with an SF-36v2PCS score > 49 (hazard ratio: 0.83; 95% CI: 0.69, 0.98; P = 0.03) were 17% less likely to terminate MMT than those with scores of ≤49. In conclusion, retention and HRQoL tended to have a bidirectional relationship, which should be considered in the development of retention and health-management programs for patients with MMT.


Subject(s)
Drug Users , Heroin Dependence/drug therapy , Methadone/therapeutic use , Adolescent , Adult , Aged , Child , China , Female , Heroin/toxicity , Heroin Dependence/pathology , Heroin Dependence/urine , Humans , Male , Methadone/adverse effects , Methadone/urine , Middle Aged , Multivariate Analysis , Opiate Substitution Treatment/adverse effects , Proportional Hazards Models , Quality of Life , Substance Abuse Treatment Centers , Young Adult
15.
Subst Abuse Treat Prev Policy ; 12(1): 33, 2017 06 26.
Article in English | MEDLINE | ID: mdl-28651618

ABSTRACT

BACKGROUND: Social support has been considered one of the most important factors of health-related quality of life (HRQoL) evaluations among different populations; however, few studies have explored the relationships of both received and perceived social support to HRQoL among patients undergoing methadone maintenance treatment (MMT). Thus, the purpose of this cross-sectional study was to clarify these relationships. METHODS: Participants were patients admitted at the two largest privately and publicly funded MMT clinics in Xi'an. The main explanatory variable was social support, both received (i.e., social network support and professional support services) and perceived (Multidimensional Scale of Perceived Social Support). The outcome was HRQoL, which was evaluated using the Short-Form 36 Health Survey version 2 (SF-36v2) and the Quality of Life Scale for Drug Addicts (QOL-DAv2.0). We carried out independent samples t-tests and multiple linear regression analysis to examine the relationships between received and perceived social support and HRQoL. RESULTS: The study findings revealed that patients with good social support had significantly higher scores on the SF-36v2 and QOL-DAv2.0 (p < 0.05). After controlling for individual characteristics, the significant factors predicting HRQoL were good family relationships, usually communicating with others, a convenient service time, appropriate treatment charges, and good perceived social support (p < 0.05). CONCLUSIONS: Our results suggest that received and perceived social support influences HRQoL among individuals receiving MMT. Thus, these variables should be considered during health management efforts and interventions directed at this patient population.


Subject(s)
Opiate Substitution Treatment/psychology , Patient Acceptance of Health Care/psychology , Quality of Life , Social Support , Adult , Aged , Analgesics, Opioid/therapeutic use , China , Cross-Sectional Studies , Female , Humans , Male , Methadone/therapeutic use , Middle Aged , Young Adult
16.
Psychol Health Med ; 22(4): 493-500, 2017 04.
Article in English | MEDLINE | ID: mdl-26987512

ABSTRACT

The study purpose was to explore relationships between perceived social support and retention in mainland Chinese patients receiving methadone maintenance treatment (MMT). Data collection included baseline information, perceived social support, and retention. A total of 1212 patients completed the cross-sectional survey; 809 (66.7%) perceived good social support and 458 (37.8%) had been re-admitted. Despite controlling baseline information, past retention did not significantly influence perceived social support. At the two-year follow-up, 527 (43.5%) patients terminated MMT. Patients with poorer perceived social support were more likely to terminate treatment, with hazard ratios of 1.31 (95% confidence interval [CI]: 1.10-1.57 without controlling baseline information and past retention) and 1.25 (95% CI: 1.04-1.51 controlling baseline information and past retention). Thus, while MMT retention does not significantly influence perceived social support, good perceived social support is a strong predictor of retention.


Subject(s)
Medication Adherence , Methadone/therapeutic use , Narcotics/therapeutic use , Opiate Substitution Treatment , Opioid-Related Disorders , Social Support , Adult , China/epidemiology , Cross-Sectional Studies , Female , Follow-Up Studies , Humans , Male , Medication Adherence/psychology , Medication Adherence/statistics & numerical data , Middle Aged , Opiate Substitution Treatment/psychology , Opiate Substitution Treatment/statistics & numerical data , Opioid-Related Disorders/drug therapy , Opioid-Related Disorders/epidemiology , Opioid-Related Disorders/psychology
17.
J Addict Med ; 11(1): 28-33, 2017.
Article in English | MEDLINE | ID: mdl-27649264

ABSTRACT

OBJECTIVES: To identify medication adherence and its influencing factors among patients of 14 methadone maintenance treatment (MMT) clinics in Xi'an, China. METHODS: Data were obtained from the National AIDS Information System-Community Methadone Maintenance Treatment. All patients registered in the system were not permitted to take methadone at home without professionals' supervision. Medication adherence was assessed using categorical (ie, dropout or retained) and continuous (ie, treatment time, methadone use time, and percentage of methadone use days) variables. Percentages of methadone use days of >90%, 50% to 90%, or <50% indicated good, moderate, and poor adherence, respectively. Multivariate Cox stepwise regression analysis was used to identify the influencing factors. RESULTS: Of the 10,398 patients, 52.2% had dropped out of MMT by December 31, 2013, whereas only 11.8% regularly visited the clinic for daily methadone (ie, >90% methadone use days) during a certain period. Protective factors were older age (>30 years); female sex; having no contact with peer drug users over the past month; no needle-sharing experience; a negative initial morphine urine test; and a higher average daily methadone dose (>20 mg) (P < 0.05). Risk factors were answering "others" for marital status; being employed; having a lack of stable income; not living with family; answering "others" for drug use type; frequently engaging in unauthorized drug use during MMT; no readmission; long travel times to the MMT clinic (>30 minutes); having no convenient MMT service time; and being dissatisfied with MMT service (P < 0.05). CONCLUSIONS: Based on our findings, multimodal intervention and management programs can be developed to improve poor medication adherence among the MMT patient population.


Subject(s)
Analgesics, Opioid/therapeutic use , Employment/statistics & numerical data , Medication Adherence/statistics & numerical data , Methadone/therapeutic use , Opiate Substitution Treatment/statistics & numerical data , Opioid-Related Disorders/drug therapy , Adult , China/epidemiology , Female , Humans , Male , Middle Aged , Opioid-Related Disorders/epidemiology
18.
Article in English | MEDLINE | ID: mdl-27916919

ABSTRACT

After validation of the widely used health-related quality of life (HRQOL) generic measure, the Short Form 36 version 2 (SF-36v2), we investigated the HRQOL and associated factors of frontline railway workers in China. Ground workers, conductors, and train drivers were selected from Ankang Precinct by using a stratified cluster sampling technique. A total of 784 frontline railway workers participated in the survey. The reliability and validity of SF-36v2 was satisfactory. The physical component summary (PCS) scores of three subgroups attained the average range for the USA general population, whereas the mental component summary (MCS) scores were well below the range. Most domains scored below the norm, except for the physical functioning (PF) domain. Among three subgroups, train drivers reported significantly lower scores on MCS and six health domains (excluding PF and bodily pain (BP)). After controlled confounders, conductors had significantly higher PCS and MCS scores than ground workers. There is heterogeneity on risk factors among three subgroups, but having long or irregular working schedules was negatively associated with HRQOL in all subgroups. SF-36v2 is a reliable and valid HRQOL measurement in railway workers in China. The frontline railway workers' physical health was comparative to American norms, whilst mental health was relatively worse. Long or irregular working schedules were the most important factors.


Subject(s)
Occupational Exposure , Quality of Life , Railroads , Adult , China , Cross-Sectional Studies , Female , Humans , Male , Mental Health , Middle Aged , Occupational Health , Reproducibility of Results , Risk Factors , Surveys and Questionnaires , Workplace
19.
BMC Cancer ; 16: 698, 2016 08 31.
Article in English | MEDLINE | ID: mdl-27576298

ABSTRACT

BACKGROUND: Breast cancer and its treatment-related adverse effects are harmful to physical, psychological, and social functioning, leading to health-related quality of life (HRQoL) impairment in patients. Many programs have been used with this population for HRQoL improvement; however, few studies have considered the physical, psychological, and social health domains comprehensively, and few have constructed multimodal standard nursing interventions based on specific theories. The purpose of this trial is to examine the effect of a health belief model (HBM)-based multimodal standard nursing program (MSNP) on HRQoL in female patients with breast cancer. METHODS: This is a two-arm single-blind cluster randomized controlled trial (cRCT) in clinical settings. Twelve tertiary hospitals will be randomly selected from the 24 tertiary hospitals in Xi'an, China, and allocated to the intervention arm and control arm using a computer-generated random numbers table. Inpatient female patients with breast cancer from each hospital will receive either MSNP plus routine nursing care immediately after recruitment (intervention arm), or only routine nursing care (control arm). The intervention will be conducted by trained nurses for 12 months. All recruited female patients with breast cancer, participating clinical staff, and trained data collectors from the 12 hospitals will be blind with respect to group allocation. Patients of the control arm will not be offered any information about the MSNP during the study period to prevent bias. The primary outcome is HRQoL measured through the Functional Assessment of Cancer Therapy-Breast version 4.0 at 12 months. Secondary outcomes include pain, fatigue, sleep, breast cancer-related lymphedema, and upper limb function, which are evaluated by a visual analogue scale, the circumference method, and the Constant-Murley Score. DISCUSSION: This trial will provide important evidence on the effectiveness of multimodal nursing interventions delivered by nurses in clinical settings. Study findings will inform strategies for scaling up comprehensive standard intervention programs on health management in the population of female patients with breast cancer. TRIAL REGISTRATION: Chictr.org.cn ChiCTR-IOR-16008253 (April 9, 2016).


Subject(s)
Breast Neoplasms/nursing , Breast Neoplasms/psychology , Quality of Life , Asian People , Female , Health Knowledge, Attitudes, Practice , Humans , Research Design , Single-Blind Method
20.
Behav Sleep Med ; 14(1): 85-99, 2016.
Article in English | MEDLINE | ID: mdl-25356919

ABSTRACT

This study examined the mediator effect of sleep hygiene practices (SHP) on relationships between sleep quality and other sleep-related factors in Chinese mainland university students using structural equation modeling analysis. Of the 413 students, 41.4% had poor sleep quality. Gender, academic stress, relaxed psychological status, good physical status, and SHP had significant direct effects on sleep quality; relaxed psychological status had significant direct effect on SHP and indirect effect on sleep quality via SHP. The direct, indirect, and total effects of gender, academic stress, relaxed psychological status, good physical status, and SHP explained 25% of the variance in sleep quality. The Chinese mainland university students had relative poor sleep quality. SHP was a mediator between sleep quality and relaxed psychological status.


Subject(s)
Sleep Initiation and Maintenance Disorders/physiopathology , Sleep Initiation and Maintenance Disorders/psychology , Sleep Medicine Specialty/methods , Sleep/physiology , Students/psychology , Universities , Adolescent , Adult , Asian People/psychology , China , Female , Humans , Male , Sex Characteristics , Sex Factors , Sleep Initiation and Maintenance Disorders/complications , Sleep Initiation and Maintenance Disorders/rehabilitation , Stress, Psychological/complications , Stress, Psychological/physiopathology , Surveys and Questionnaires , Young Adult
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