1.
Pharmazie
; 66(12): 933-5, 2011 Dec.
Article
in English
| MEDLINE
| ID: mdl-22312697
ABSTRACT
The polymorphism of flucloxacillin sodium has not been discussed sufficiently so far. Flucloxacillin sodium which was crystallized with different solvents, was found to exist in amorphism and three crystal forms (I, II, III). This results were confirmed by infra-red (IR) spectra, thermogravimetry (TG), X-ray diffraction analysis (XRD) and equilibrium solubility. It is noticed that form III has very good solubility in phosphate buffer solution, with an average solubility of 0.86 g (20-40 degrees C). However, more efforts are needed to carry out and decide whether this form can be used for industrial production.
Subject(s)
Anti-Bacterial Agents/chemistry , Floxacillin/chemistry , Differential Thermal Analysis , Hydrogen-Ion Concentration , Indicators and Reagents , Isomerism , Solubility , Spectrophotometry, Infrared , Thermogravimetry , X-Ray Diffraction
2.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
; 30(6): 726-8, 2005 Dec.
Article
in Chinese
| MEDLINE
| ID: mdl-16708821
Subject(s)
Blood Platelets/cytology , Bone Marrow Cells/cytology , Fibroblasts/cytology , Megakaryocytes/cytology , Thrombocytopenia/therapy , Animals , Cell Differentiation , Cells, Cultured , Culture Media, Conditioned , Cyclophosphamide , Female , Male , Mice , Stem Cells/cytology , Thrombocytopenia/chemically induced
3.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
; 21(6): 377, 2003.
Article
in Chinese
| MEDLINE
| ID: mdl-15108560
