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1.
World J Clin Cases ; 11(28): 6763-6773, 2023 Oct 06.
Article in English | MEDLINE | ID: mdl-37901016

ABSTRACT

BACKGROUND: Uterine fibroids, are prevalent benign tumors affecting women of reproductive age. However, surgical treatment is often necessary for symptomatic hysteromyoma cases. This study examines the impact of humanized nursing care on reducing negative emotions and postoperative complications in patients receiving hysteromyoma surgery. AIM: To investigate the impact of humanized nursing care on patients undergoing hysteromyoma surgery. METHODS: Among patients who underwent hysteromyoma surgery at the Fudan University Affiliated Obstetrics and Gynecology Hospital, 200 were randomly assigned to either the control group (n = 100) or the humanized nursing care group (n = 100). The control group received traditional nursing care, while the humanized nursing care group received a comprehensive care plan encompassing psychological support, pain management, and tailored rehabilitation programs. In addition, anxiety and depression levels were assessed using the hospital anxiety and depression scale preoperatively and postoperatively. Postoperative complications were evaluated during follow-up assessments and compared between both groups. RESULTS: The humanized nursing care group demonstrated a significant decrease in anxiety and depression levels compared to the control group (P < 0.05). The rate of postoperative complications, including infection, bleeding, and deep venous thrombosis, was also markedly lower in the humanized nursing care group (P < 0.05). CONCLUSION: Humanized nursing care can effectively alleviate negative emotions and reduce the incidence of postoperative complications in patients undergoing hysteromyoma surgery. This approach should be considered a crucial component of perioperative care for these patients. Further research may be needed to explore additional benefits and long-term outcomes of implementing humanized nursing care in this population.

2.
Anal Chim Acta ; 1279: 341747, 2023 Oct 23.
Article in English | MEDLINE | ID: mdl-37827661

ABSTRACT

Determination of ferri ions in environment and human bodies is very important for environmental protection and disease diagnosis. Recently, conjugated microporous polymers (CMPs) used for fluorescence sensing metal ions have attracted much attention, but this technique is done in organic solvents. In this study, the two new fluorescein-based CMPs named FLEDOT and FLBTh were synthesized by "greener method", direct arylation polymerization, with tetraiodofluorescein sodium salt (TIFS) and 3,4-ethylenedioxy thiophene or 2,2'-bithiophene. Pleasely, the prepared fluorescein-based CMPs can fluorescently sense for Fe3+ in water with high sensitivity and selectivity. The quenching constants (KSV) of FLEDOT and FLBTh are 1.51 × 104 and 1.09 × 104 L mol-1, and the limits of detection (LODs) as low as 1.99 × 10-10 and 2.75 × 10-10 mol L-1, which are comparable to the sensitivity found in organic solvents' dispersions such as N,N-dimethylformamide (DMF)' dispersions. UV-Vis absorption spectra show that the fluorescence quenching mechanisms of Fe3+ are absorption competition quenching process and energy transfer process.

3.
Mater Sci Eng C Mater Biol Appl ; 67: 326-335, 2016 Oct 01.
Article in English | MEDLINE | ID: mdl-27287128

ABSTRACT

Hydrophilic porous polymer scaffolds have shown great application in drug controlled release, while their mechanical properties and release efficiency still need further improvement. In the current study, the porous scaffolds of polyvinyl alcohol (PVA) prepared by quenching in liquid nitrogen and freeze drying method from different original concentration aqueous solutions were fabricated. Among different PVA scaffolds, the scaffold stemming from 18wt.% PVA aqueous solution exhibited the best mechanical properties, 10.5 and 1.54MPa tensile strengths for the dry and hydrogel states respectively. The inner morphology of such PVA scaffold was unidirectional honeycomb-like structure with average microchannel section of 0.5µm, and the scaffold showed porosity of 71% and rather low ciprofloxacin (Cip) release efficiency of 54.5%. Then poly(ethylene glycol) (PEG) was incorporated to enhance the Cip release efficiency. The release efficiency reached 89.3% after introducing 10wt.% PEG, and the mechanical properties of scaffold decreased slightly. Various characterization methods demonstrated that, adding PEG could help to enlarge the microchannel, create extra holes on the channel walls, weaken the interaction between PVA chains and Cip, and miniaturize the crystal size of Cip. All these effects benefit the dissolution and diffusion of Cip from scaffold, increasing its release capability. Moreover, based on biocompatible material composition, PVA/PEG scaffold is a non-cytotoxicity and have been verified that it can promote cell growth. And PVA/PEG scaffolds loaded with Cip can completely inhibit the growth of microorganism because of Cip sustaining release. The PVA scaffold would have a good potential application in tissue engineering, demanding high strength and well drug release capability.


Subject(s)
Ciprofloxacin/pharmacology , Drug Liberation , Polyvinyl Alcohol/chemistry , Tissue Scaffolds/chemistry , Animals , Anti-Infective Agents/pharmacology , Biocompatible Materials/pharmacology , Calorimetry, Differential Scanning , Cell Death/drug effects , Ciprofloxacin/chemistry , Escherichia coli/drug effects , Freeze Drying , Hydrogel, Polyethylene Glycol Dimethacrylate/chemistry , Kinetics , Mice , NIH 3T3 Cells , Polyethylene Glycols/chemistry , Porosity , Solutions , Spectroscopy, Fourier Transform Infrared , X-Ray Diffraction
4.
Zhonghua Zhong Liu Za Zhi ; 30(12): 901-4, 2008 Dec.
Article in Chinese | MEDLINE | ID: mdl-19173989

ABSTRACT

OBJECTIVE: To investigate the characteristics of freshly resected laryngeal carcinoma by Fourier transform infrared spectroscopy (FTIR). METHODS: FTIR was applied to the study of the cancerous tissues and adjacent normal tissues in 32 patients. RESULTS: Compared with pathological diagnosis results, one benign specimen was classified as a malignant, the accuracy was 98.4%. Significant differences were seen in the FTIR spectra between the normal and malignant laryngeal tissues. The peak at 1085 cm(-1) shift to 1114 cm(-1) showed that the relative contents of DNA in laryngeal carcinoma cells was increased. The peak at 1397 cm(-1) was stronger than 1451 cm(-1) in normal tissues, while it was not obvious in cancer tissues. I(2926)/I(2870) in carcinoma cells was lower than that in normal tissues. The wave numbers of the bands of amide I and amide II, symmetric and asymmetric stretching bands of CH(3), stretching vibration bands of C-OH and NH band were shifted to higher number in cancer tissues. CONCLUSION: The study shows that the malignant and normal laryngeal tissues have different FTIR spectra, which are mainly due to changes in protein, nucleic acid and phospholipids. FTIR may become a new method for the diagnosis of laryngeal carcinoma in clinical practice.


Subject(s)
Laryngeal Neoplasms/chemistry , Laryngeal Neoplasms/diagnosis , Larynx/chemistry , Neoplasm Proteins/analysis , Spectroscopy, Fourier Transform Infrared/methods , Humans , Laryngeal Neoplasms/pathology , Larynx/pathology , Nucleic Acids/analysis , Phospholipids/analysis
5.
Sci Total Environ ; 383(1-3): 164-73, 2007 Sep 20.
Article in English | MEDLINE | ID: mdl-17570464

ABSTRACT

To understand the influence of aerosol particles and meteorological conditions on visual range in Jinan, the capital of Shandong Province, China, PM(2.5) and PM(10) samples were collected from November 2004 to September 2005. The mass concentrations of PM(2.5) and PM(10), concentrations of water-soluble ions in PM(2.5) and concentrations of black carbon (BC) in the atmosphere were analyzed. The decrease of visual range in Jinan results from the combined influence of PM(2.5), PM(10) and meteorological conditions. For the period studied, the average light extinction coefficient, b(ext), which was estimated from an equation developed by the IMPROVE network was 292 Mm(-1). Ammonium sulfate was the major contributor to visual range impairment, accounting for 41%, while ammonium nitrate, particulate organic matter (POM) and BC made comparable contributions accounting for 20%, 22% and 18%, respectively. This highlights the significance of secondary particles ((NH(4))(2)SO(4), NH(4)NO(3), POM) in visual range impairment in Jinan. The data from this study are also compared with the long-term variations of visual range in Jinan from 1961 to 2005.


Subject(s)
Air Pollutants/analysis , Particulate Matter/analysis , Vision, Ocular , Carbon/analysis , China , Environmental Monitoring , Humidity , Nitrates/analysis , Particle Size , Quaternary Ammonium Compounds/analysis , Sulfates/analysis , Temperature , Wind
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