Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
Int J Mol Med ; 53(4)2024 04.
Article in English | MEDLINE | ID: mdl-38391090

ABSTRACT

The vestibular system may have a critical role in the integration of sensory information and the maintenance of cognitive function. A dysfunction in the vestibular system has a significant impact on quality of life. Recent research has provided evidence of a connection between vestibular information and cognitive functions, such as spatial memory, navigation and attention. Although the exact mechanisms linking the vestibular system to cognition remain elusive, researchers have identified various pathways. Vestibular dysfunction may lead to the degeneration of cortical vestibular network regions and adversely affect synaptic plasticity and neurogenesis in the hippocampus, ultimately contributing to neuronal atrophy and cell death, resulting in memory and visuospatial deficits. Furthermore, the extent of cognitive impairment varies depending on the specific type of vestibular disease. In the present study, the current literature was reviewed, potential causal relationships between vestibular dysfunction and cognitive performance were discussed and directions for future research were proposed.


Subject(s)
Cognitive Dysfunction , Vestibular Diseases , Humans , Cognition/physiology , Cognitive Dysfunction/etiology , Quality of Life , Spatial Memory/physiology , Vestibular Diseases/psychology
2.
ACS Appl Mater Interfaces ; 14(42): 47542-47548, 2022 Oct 26.
Article in English | MEDLINE | ID: mdl-36228176

ABSTRACT

Precise adjustment of the metal site structure in single-atom catalysts (SACs) plays a key role in addressing the oxygen evolution reaction (OER). Herein, we report the synthesis of O-doped Ni SACs anchored on porous graphene-like carbon (Ni-O-G) using molten salts (ZnCl2 and NaCl) as templates, in which the unique Ni-O4 structure serves as the active sites. Ni-O-G, with an overpotential of only 238 mV (@ 10 mA cm-2), is one of the more advanced catalysts. An array of characterizations and density functional theory calculations show that the Ni-O4 coordination enables Ni to be closer to the Fermi level compared to traditional Ni-N4, enhancing the electronic metal-support interaction to facilitate OER kinetics. Thus, this work offers an alternative strategy for the structural modulation of Ni SACs and the effect of different coordination elements with the same atomic coordination structure on the intrinsic OER activity.

3.
J Colloid Interface Sci ; 605: 528-536, 2022 Jan.
Article in English | MEDLINE | ID: mdl-34340037

ABSTRACT

The rational design and preparation of advanced electrocatalysts for the hydrogen evolution reaction (HER) under alkaline conditions is the key to achieving sustainable hydrogen production. Herein, a new type of nitrogen-doped porous carbon nanosheets (NPCN) loaded with platinum group metals (Pd, Pt or Ru) were prepared. The introduction of melamine not only realized the doping of N-species, but also optimized the morphology and surface functional groups of the prepared catalysts. The prepared Pd-NPCN, Pt-NPCN and Ru-NPCN with a metal loading of about 10 wt% showed outstanding HER activity (21, 9 and 11 mv at 10 mA cm-2 current density), small Tafel slopes (49, 30 and 30 mV dec-1) and good stability in 1.0 M KOH. In addition, the mechanism of the introduction of melamine to improve the catalytic performance of HER was also discussed. Therefore, this work provides promising alternatives to traditional Pt-based catalysts, and is instructive for the design of high-efficiency alkaline HER catalysts.

SELECTION OF CITATIONS
SEARCH DETAIL
...