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1.
J Med Virol ; 93(4): 2046-2055, 2021 04.
Article in English | MEDLINE | ID: mdl-32997344

ABSTRACT

To date, the coronavirus disease 2019 (COVID-19) has a worldwide distribution. Risk factors for mortality in critically ill patients, especially detailed self-evaluation indicators and laboratory-examination indicators, have not been well described. In this paper, a total of 192 critically ill patients (142 were discharged and 50 died in the hospital) with COVID-19 were included. Self-evaluation indicators including demographics, baseline characteristics, and symptoms and detailed lab-examination indicators were extracted. Data were first compared between survivors and nonsurvivors. Multivariate pattern analysis (MVPA) was performed to identify possible risk factors for mortality of COVID-19 patients. MVPA achieved a relatively high classification accuracy of 93% when using both self-evaluation indicators and laboratory-examination indicators. Several self-evaluation factors related to COVID-19 were highly associated with mortality, including age, duration (time from illness onset to admission), and the Barthel index (BI) score. When the duration, age increased by 1 day, 1 year, BI decreased by 1 point, the mortality increased by 3.6%, 2.4%, and 0.9% respectively. Laboratory-examination indicators including C-reactive protein, white blood cell count, platelet count, fibrin degradation products, oxygenation index, lymphocyte count, and d-dimer were also risk factors. Among them, duration was the strongest predictor of all-cause mortality. Several self-evaluation indicators that can simply be obtained by questionnaires and without clinical examination were the risk factors of all-cause mortality in critically ill COVID-19 patients. The prediction model can be used by individuals to improve health awareness, and by clinicians to identify high-risk individuals.


Subject(s)
COVID-19/mortality , Critical Illness/mortality , Diagnostic Self Evaluation , Adult , Aged , Aged, 80 and over , China , Female , Humans , Male , Middle Aged , Multivariate Analysis , Prognosis , Risk Factors
2.
Sensors (Basel) ; 20(14)2020 Jul 13.
Article in English | MEDLINE | ID: mdl-32668618

ABSTRACT

Friction is a crucial factor affecting air accident occurrence on landing or taking off. Tire-runway friction directly contributes to aircraft stability on land. Therefore, an accurate friction estimation is a rising issue for all stakeholders. This paper summarizes the existing measurement methods, and a multi-sensor information fusion scheme is proposed to estimate the friction coefficient between the tire and the runway. Acoustic sensors, optical sensors, tread sensors, and other physical sensors form a sensor system that is used to measure friction-related parameters and fuse them through a neural network. So far, many attempts have been made to link the ground friction coefficient with the aircraft braking friction coefficient. The models that have been developed include the International Runway Friction Index (IRFI), Canada Runway Friction Index (CRFI), and other fitting models. Additionally, this paper attempts to correlate the output of the neural network (estimated friction coefficient) with the correlation model to predict the friction coefficient between the tire and the runway when the aircraft brakes. The sensor system proposed in this paper can be regarded as a mobile weather-runway-tire system, which can estimate the friction coefficient by integrating the runway surface conditions and the tire conditions, and fully consider their common effects. The role of the correlation model is to convert the ground friction coefficient to the grade of the aircraft braking friction coefficient and the information is finally reported to the pilots so that they can make better decisions.

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