ABSTRACT
Aneurysmal bone cyst (ABC) is a benign, distending, osteolytic and locally aggressive bone tumor that is mostly associated with trauma. Approximately 1% of bone tumors are ABCs, which are most prevalent in adolescents and are usually detected in the spine and long tubular bones. The diagnosis of ABC mainly relies on histopathology, malignant transformation is rare, and the chance of malignancy increases if there are multiple recurrences. Due to the rarity of reports of malignant transformation of ABCs into osteosarcoma, there is still considerable debate on the appropriate treatment strategy. The current paper presents a case of aneurysmal bone cyst malignant to osteosarcoma and the therapeutic measures to provide expertise for the diagnosis and treatment of ABCs that are malignant to osteosarcoma.
ABSTRACT
The 2018 tropical cyclone (TC) season over the western North Pacific (WNP) underwent two extreme situations: 18 TCs observed during June-August (JJA) and ranked the second most active summer in the satellite era; only 5 TCs that occurred during September-October (SO), making it the most inactive period since the late 1970s. Here we attribute the two extreme situations based on observational analyses and numerical experiments. The extremely active TC activity and northward shift of TC genesis during JJA of 2018 can be attributed to the WNP anomalous low-level cyclone, which is due primarily to El Niño Modoki and secondarily to the positive phase of the Pacific Meridional Mode (PMM). Overall, the extremely inactive TC activity during SO of 2018 is due to the absence of TC formation over the South China Sea and Philippine Sea, which can be attributed to the in-situ anomalous low-level anticyclone associated with the positive phase of the Indian Ocean Dipole, although the positive PMM phase and El Niño Modoki still hold.
