ABSTRACT
OBJECTIVE: To evaluate the application of sputum suction by fiberoptic bronchoscope to patients with severe pneumonia and its effect on inflammatory factors. METHODS: One hundred and three patients with severe pneumonia were randomly divided into the control group (n=52) and the observation group (n=51). Both groups were given anti-infection, antitussive and expectoration treatment. The observation group was treated with sputum suction by fiberoptic bronchoscope. The control group was treated with a vibration sputum extractor. The clinical efficacy, clinically related indexes, inflammatory factors, blood gas indexes and the Acute Physiology and Chronic Health Evaluation (APACHE II) score of the two groups were compared. RESULTS: After the treatment, the total effective rate of the observation group was higher than that of the control group; the length of stay in ICU, mechanical ventilation time and duration of antibiotics of the observation group were shorter than those of the control group (all P<0.05). After the treatment, the serum levels of CRP, TNF-α and PCT and APACHE II scores in the two groups were all decreased, while PaO2, SaO2 and OI were increased; the changes in the observation group were more significant than the control group (all P<0.05). CONCLUSION: Sputum suction and lavage by fiberoptic bronchoscope can significantly control the body's inflammatory reaction state in patients with severe pneumonia, improve their blood oxygen and promote the treatment effect.
