ABSTRACT
OBJECTIVE: To explore the value of Wisconsin Card Sorting Test (WCST) in evaluating the recognition impairment after traumatic brain injury (TB1). METHODS: WCST and Wechsler Adult Intelligence Scale Revised in China (WAIS-RC) were adopted to assess the cognitive function in 186 patients with brain injury (experimental group) and 180 healthy volunteers (control group), respectively. The cognition between the experimental group and the control group was compared. The correlation between WCST and IQ was analyzed. The correlation between age, education level, the severity of TBI and the executive function were also analyzed. RESULTS: (1) The performances of WAIS-RC and WCST in the experimental group were significantly worse than that of the control group. (2) There were significantly negative correlation between the performance of total errors, percentage of preservative errors, percentage of random errors, response number on first category and IQ (P < 0.05). While there were significantly positive correlation between the categories completed, percentage of conceptual level and IQ (P < 0.05). (3) There was significantly negative correlation between percentage of conceptual level and the severity of TBI. While there were significantly positive correlation between percentage of preservative errors, percentage of random errors, response number on first category and the severity of TBI. CONCLUSION: WCST could be an important method in evaluating cognition of patients with brain injury.
Subject(s)
Brain Injuries/complications , Brain/pathology , Cognition Disorders/diagnosis , Cognition Disorders/etiology , Executive Function/physiology , Neuropsychological Tests , Adolescent , Adult , Aged , Brain Injuries/pathology , Brain Injuries/psychology , Case-Control Studies , Female , Humans , Male , Middle Aged , Multivariate Analysis , Predictive Value of Tests , Psychiatric Status Rating Scales , Psychometrics , Reproducibility of Results , Severity of Illness Index , Task Performance and Analysis , Wechsler Scales , Young AdultABSTRACT
OBJECTIVE: To evaluate the expression of Bcl-2 protein after brain concussion. METHODS: Expression levels of Bel-2 protein in cortex, pontine and cerebellum of rats were investigated using immunohistochemistry. RESULTS: There was no expression of Bcl-2 protein in control group seen. The expression of Bcl-2 protein in brain concussion groups was detected at l hour, and the expression level reached its peak 4 days after the concussion and then declined gradually. CONCLUSION: Our findings suggest that the detection of Bel-2 protein could be an indicator for diagnosis of brain concussion and for estimation of the post injury time interval.
Subject(s)
Brain Concussion/metabolism , Brain Stem/metabolism , Cerebral Cortex/metabolism , Proto-Oncogene Proteins c-bcl-2/metabolism , Animals , Brain/metabolism , Brain/pathology , Brain Stem/pathology , Cerebral Cortex/pathology , Contusions/metabolism , Contusions/pathology , Disease Models, Animal , Female , Immunohistochemistry , Male , Neurons/metabolism , Neurons/pathology , Rats , Rats, Sprague-Dawley , Time FactorsABSTRACT
OBJECTIVE: To assess the clinical application of spiral CT 3D reconstruction in forensic diagnosis of rib fracture. METHODS: Thirty-five cases of rib fractures were collectively studied by X-ray, regular CT scan, and adoptive 3D reconstruction with spiral CT. RESULTS: Clear and stereoscopic images of rib fractures without interference of the surrounding soft tissue were obtained in all of 35 cases examined. CONCLUSION: Spiral CT 3D reconstruction could be a valuable means in forensic diagnosis of rib fracture.
Subject(s)
Forensic Pathology/methods , Rib Fractures/diagnostic imaging , Ribs/diagnostic imaging , Tomography, Spiral Computed/methods , Adolescent , Adult , Aged , Female , Humans , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Male , Middle Aged , Ribs/pathology , Thoracic Injuries/diagnostic imaging , Young AdultABSTRACT
Integrating the healthcare enterprise (IHE) is a developing general norm in medical informatics especially in the field of radiology, which is independent of the manufacturers and has been accepted by a number of manufacturers and systems. In this paper, the authors provide a brief overview of IHE with the integration profiles of IHE technical framework being particularly elaborated.
