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Article in Russian | MEDLINE | ID: mdl-16438381

ABSTRACT

Neisseria-induce different infections, but many representatives of this genus are saprophytes. In this connection it is important to evaluate the species, and for N. meningitidis also group specificity of the immunological diagnostics of meningococcal infection and gonorrhea. In this work the specificity of the antigen-binding lymphocyte test was studied in experiments with the immunization of rabbits and the examination of patients. In the tests of indirect rosette-formation and its inhibition the role of antigenic relationships between different pathogenic and nonpathogenic Neisseria was excluded and the species and group specificity of our Neisseria immunoreagents, used in the diagnostics of meningococcal infection and gonorrhea, was proved.


Subject(s)
Bacterial Typing Techniques/methods , Neisseria/classification , Neisseriaceae Infections/diagnosis , Rosette Formation/methods , Animals , Antigens, Bacterial/immunology , Humans , Lymphocyte Count , Lymphocytes/immunology , Neisseria/immunology , Neisseriaceae Infections/blood , Rabbits , Species Specificity
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