ABSTRACT
Phenothiazine and its derivatives have a number of properties that contribute to their wider practical use in the production of biologically active substances, drugs, dyes, etc. Therefore, the synthesis and study of new compounds is of great relevance. The aim of this work was to investigate the antioxidant activity of a number of new phenothiazine derivatives. The patterns of electroreduction of oxygen and its radicals in the presence of phenothiazine derivatives in aqueous ethanol media were studied by voltammetry. The influence of various factors on antioxidant activity was considered by the methods of experiment planning. The optimal conditions for the manifestation of the antioxidant activity of phenothiazine derivatives have been found, which seems to be relevant since it opens up new possibilities for their further use as complex preparations with antioxidant activity, including in psychiatric practice.
ABSTRACT
Heavy metals are among the most common pollutants affecting biological systems when ingested with drinking water and food. Heavy metal ions are capable of bioaccumulation in a human body and could cause various metabolic disorders. Here we present the results of using a unique glauconite from the Barguzinsky deposit as an adsorbent for heavy metals. The physicochemical properties of glauconite samples, including the specific surface area, specific pore volume, zeta potential, thermal and elemental analyses and scanning electron microscopy of the surface were studied for different fraction sizes. The sorption properties of the glauconite samples were studied under static conditions for extraction of iron and manganese ions from model solutions. Analysis of the content of the detected ions in solutions and filtrates was performed by the methods of stripping voltammetry. We revealed high sorption properties of glauconite for iron elimination, but comparatively lower ones in removing manganese.
