ABSTRACT
This paper describes the results of an original study into the systemic and local immunity in 25 patients with trophic venous ulcers. The authors discovered a number of significant parameters demonstrating the influence of the immune status on the formation of venous ulcers and tempo of their healing. They revealed previously unknown relationships between the immune status, clinical manifestations arid natural history of venous ulcers. Presented herein are the first results of the local use of the immunomodulator gepon and evidence for its efficacy in the treatment of chronic trophic venous ulcers.
Subject(s)
CD8 Antigens/immunology , Cytokines/immunology , Leg Ulcer/drug therapy , Leg Ulcer/immunology , T-Lymphocytes/immunology , Varicose Ulcer/drug therapy , Varicose Ulcer/immunology , Adult , Aged , Biomarkers , Female , Humans , Immunologic Factors/therapeutic use , Male , Middle Aged , Oligopeptides/therapeutic useABSTRACT
This paper describes the results of the study into the prevalence of chronic venous diseases among industrial workers of Moscow. It has been established that chronic venous diseases are fairly prevalent among industrial workers. They affect the people of both sexes (67.5% of women and 50.4% of men), varying age and occupation. With age their incidence rises. The most significant risk factors of the onset of chronic venous diseases include hereditary predisposition, pregnancy and birth, overweight, and intake of hormonal contraceptives. The study has demonstrated that in most cases, such patients are not rendered medical assistance.
Subject(s)
Industry , Lower Extremity/blood supply , Occupational Diseases/diagnosis , Occupational Diseases/physiopathology , Venous Insufficiency/physiopathology , Adult , Age Distribution , Aged , Catchment Area, Health , Female , Humans , Incidence , Lower Extremity/diagnostic imaging , Lower Extremity/physiopathology , Male , Middle Aged , Occupational Diseases/epidemiology , Risk Factors , Russia/epidemiology , Ultrasonography, Doppler , Venous Insufficiency/diagnosis , Venous Insufficiency/epidemiologyABSTRACT
This paper describes the first results of endovasal laser obliteration of the greater sephenous vein in two patient groups (n=40) math varicosis. In 15 cases (control group), laser obliteration was employed during routine operation as an alternative to phlebectomy according to Babcock following crossectomy. In 25 patients (the main group), operation was performed without ligation of the saphenofemoral anastomosis. After puncture and catheterization according to Seldinger the greater saphenous vein was exposed to thermal action over the length from the osteal valve to the upper third of the leg. The follow up of the patients amounted to 12 months. The results obtained in the main patient group seem most interesting. Stable elimination of truncal varicosis could be attained in more than 90% of cases, which was associated with quick medicosocial rehabilitation, the minimal number of complications and an excellent cosmetic effect.
Subject(s)
Laser Therapy/instrumentation , Saphenous Vein/surgery , Varicose Veins/surgery , Vascular Surgical Procedures/methods , Adult , Angiography/methods , Female , Humans , Male , Middle Aged , Phlebitis/complications , Phlebitis/diagnosis , Phlebitis/surgery , Varicose Veins/complications , Varicose Veins/diagnosisABSTRACT
Venous trophic ulcers comprise an important social and medical problem. Conventional therapy includes initial healing of ulceration with consequent surgical intervention. Persistent or recurrent venous ulcers elicit irreversible changes in skin, subcutaneous fat and fasciae making impossible complete success of standard autodermoplasty. We present our experience in shave therapy with autodermoplasty and simultaneous correction of hemodynamic disturbances for this cohort of patients. Study results have demonstrated that in patients with chronic venous trophic ulcers and manifested lipodermatofasciosclerosis shave therapy suggests an optimal volume of intervention.
Subject(s)
Dermatology/methods , Leg Ulcer/therapy , Lipectomy/methods , Wound Healing , Adult , Female , Humans , Leg Ulcer/etiology , Male , Middle Aged , Varicose Veins/complicationsSubject(s)
Occlusive Dressings , Varicose Ulcer/drug therapy , Waxes , Adolescent , Adult , Aged , Analgesics/administration & dosage , Analgesics/adverse effects , Analgesics/therapeutic use , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/adverse effects , Anti-Bacterial Agents/therapeutic use , Drug Carriers , Female , Humans , Male , Middle Aged , Occlusive Dressings/adverse effects , Treatment Outcome , Varicose Ulcer/physiopathology , Wound Healing/drug effects , Wound Healing/physiologyABSTRACT
This paper presents an experience gained with the treatment of 39 patients with lower extremity varicosity using a novel method of phlebosclerosing treatment, named the foam-form technique. The authors give a detailed description of the treatment modality, analyze the short- and long-term results. The conclusion is drawn that the given method is safe and effective. The emphasis is laid on the necessity of an objective evaluation of the collective experience with the use of the foam-form technique.
