[The role of free radical oxidation processes in the morphogenesis of axons of regenerating nerves]. / Rol' protsessov svobodnoradikal'nogo okisleniia v morfogeneze aksonov regeneriruiushchego nerva.

Patterns of lipid peroxidation as well as morphogenesis and differentiation of newly formed axons in regenerating nerve were studied in guinea pigs with experimental syndrome of peroxidation which developed after local gamma-irradiation of right hind legs of the animals maintained on the diet containing no antioxidants. The diet without antioxidants increased the inhibitory and impairing effects of the radiation on differentiation of the regenerating nerve and also caused similar effects in control experiments without the irradiation.

[Postradiation disorders of peripheral nerve regeneration and role of free-radical oxidation products in their origin]. / Postradiatsionnye narusheniia regeneratsii perifericheskogo nerva i rol' produktov svobodnoradikal'nogo okisleniia v ikh vozniknovenii.

Long-term keeping of guinea pigs on antioxidant-free diet was shown to increase the rate of free-radical oxidation processes after local exposure to 20 Gy gamma-radiation. Alimentary antioxidant deficiency enhanced new formation and growth of young axons, inhibited myelinization both in the exposed and contralateral nonirradiated nerves being regenerated after ligating thereof.