1.
Chirality
; 2(2): 124-7, 1990.
Article
in English
| MEDLINE
| ID: mdl-2400638
ABSTRACT
A new urea-bonded chiral stationary phase has been developed in our laboratory. This bonded phase has been shown to resolve N-terminal substituted amino acids and the carboxyl derivatized anti-inflammatory drugs. Typical alpha-value for dinitrobenzoyl phenylglycine was 1.7. Values for derivatized ibuprofen, naproxen, and fenoprofen were 2, 1.84, and 1.6, respectively. Further application of these studies to biologically active compounds such as peptides and drugs is in progress.
Subject(s)
Acids/isolation & purification , Amines/isolation & purification , Anti-Inflammatory Agents, Non-Steroidal/isolation & purification , Chemical Phenomena , Chemistry , Fenoprofen/analogs & derivatives , Fenoprofen/isolation & purification , Ibuprofen/analogs & derivatives , Ibuprofen/isolation & purification , Naproxen/analogs & derivatives , Naproxen/isolation & purification , Spectrophotometry, Infrared , Stereoisomerism , Urea
2.
Clin Chem
; 19(11): 1303-4, 1973 Nov.
Article
in English
| MEDLINE
| ID: mdl-4758608
Subject(s)
Magnesium/blood , Barium , Calcium , Drug Stability , Evaluation Studies as Topic , Gluconates , Hydrogen-Ion Concentration , Methods , Photometry , Solubility , Spectrophotometry, Atomic , Strontium , Time Factors , Water
3.
Clin Chem
; 18(5): 446-8, 1972 May.
Article
in English
| MEDLINE
| ID: mdl-5019118
4.
Clin Chem
; 17(9): 833-40, 1971 Sep.
Article
in English
| MEDLINE
| ID: mdl-5571483
