1.
Arthritis Rheum
; 29(10): 1269-73, 1986 Oct.
Article
in English
| MEDLINE
| ID: mdl-3490264
ABSTRACT
In 155 women with systemic lupus erythematosus, there were no significant differences in the rates of fertility or adverse fetal outcome between the 47 (30%) with serum anti-SS-A antibody and the 108 without anti-SS-A, except in the frequency of congenital heart block. This complication occurred in 6 of 96 pregnancies in women with anti-SS-A and was associated with high-titer maternal antibody. The overall risk of a woman with lupus having an infant with congenital heart block was estimated to be 1:60, but the risk was considerably higher (1:20) if anti-SS-A antibody was present.
Subject(s)
Antibodies, Antinuclear/analysis , Lupus Erythematosus, Systemic/complications , Pregnancy Complications/immunology , Abortion, Spontaneous/etiology , Female , Fetal Death , Heart Block/congenital , Humans , Infant, Newborn , Lupus Erythematosus, Systemic/immunology , Obstetric Labor, Premature/etiology , Pregnancy , Retrospective Studies , Risk
2.
Nurs Clin North Am
; 19(4): 673-95, 1984 Dec.
Article
in English
| MEDLINE
| ID: mdl-6393067