ABSTRACT
INTRODUCTION: Long-term domiciliary oxygen therapy (LTOT) is part to of pulmonary care system. Uniform qualification criteria and methods of follow-up for patients undergoing LTOT have been adopted. There are 63 LTOT centres located in Poland run by specialists in pulmonology. On the occasion of 20 years of LTOT in Poland, an analysis of its development, number of patients treated, diagnoses, survival and equipment was performed. MATERIAL AND METHODS: Data were taken from structurized LTOT centres reports. RESULTS AND CONCLUSIONS: A history of LTOT may be divided into 3 periods, steady grow in the years 1986-1991, stagnation between 1992-2000 and rapid grow in the last 3 years. On 01.01.2006 there was 2601 patients receiving LTOT therapy. The most common diagnosis was COPD (85%) followed by kyphoscolisis (5%), TB sequels (4.6%), IPF (3.6%) and other rare diseases. Treatment is reimbursed by the National Health System. Oxygen is administered via an oxygen concentrator. Due to insufficient resources from the NHS the needs for LTOT treatment are not fulfilled. There are 8.4 patients treated with LTOT per 100 000 people, with large regional differences ranging from 3.7 to 14.9/100 000. The most frequent cause of death in patients receiving LTOT treatment was exacerbation of respiratory failure (71.3%), followed by sudden death (5.1%), myocardial infarction or pulmonary embolism (4.4%), lung cancer (4%) and other or not known causes (15.2%). Survival in patients receiving LTOT treatment from the years 1986-1995 was rather short: 54.6% survived less than 3 years, 3-4 years survived 13.3%, 4-5 years 11.3% and more than 5 years survived 19.7% of treated patients.
Subject(s)
Home Care Services/statistics & numerical data , Hypoxia/therapy , Lung Diseases, Obstructive/epidemiology , Lung Diseases, Obstructive/therapy , Oxygen Inhalation Therapy/statistics & numerical data , Humans , Hypoxia/mortality , Long-Term Care/statistics & numerical data , Lung Diseases, Obstructive/mortality , National Health Programs/statistics & numerical data , Oxygen Inhalation Therapy/methods , Poland , Pulmonary Disease, Chronic Obstructive/epidemiology , Pulmonary Disease, Chronic Obstructive/therapyABSTRACT
We report the successful management of a 25 year-old woman diagnosed in the second trimester of her pregnancy with chronic myelogenous leukemia (CML). She was treated with leukapheresis until her delivery at 38 weeks of gestation. The procedure was without significant adverse effects on the patient or the fetus. Following induced vaginal delivery, the patient underwent allogeneic bone marrow transplantation from her HLA-matched brother and is presently disease free 13 months following her transplant.