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1.
J Arthroplasty ; 31(10): 2291-4, 2016 10.
Article in English | MEDLINE | ID: mdl-26897487

ABSTRACT

BACKGROUND: Few publications have raised concern with the safety of the anterior approach (AA) to total hip arthroplasty (THA). The purpose of this study is to report the early complications with AA THA in a combined, multicenter patient population from three different institutions. METHODS: The study cohort consisted of 5090 consecutive primary procedures in 4473 patients who had undergone THA utilizing the anterior approach between August 2006 and July 2013. Surgeries were performed by five surgeons at three sites that maintain prospective databases. Preoperative, intraoperative, and postoperative data were recorded on all patients. Demographic data including age, gender, and BMI were queried, as well as all intraoperative and postoperative complications in the first 90 days. RESULTS: The 5090 patients had a mean body mass index of 27.5, and mean age of 63.6 years. The overall 90-day complication rate was 1.9%. There were 41 intraoperative femur fractures including 29 calcar fractures, 9 greater trochanter fractures and 3 femoral shaft fractures. There were 7 postoperative femur fractures including 3 greater trochanter fractures, 2 calcar fractures, and 2 femur fractures. Other complications included 15 superficial infections, 5 deep infections, 12 dislocations, 8 hematomas, 3 cases of cellulitis, 2 sciatic nerve palsies, 1 peroneal nerve palsy, and intrapelvic bleed. The nonsurgical complication rate was 1.4%. Deep vein thrombosis occurred in 0.3% of cases. CONCLUSION: This large multicenter study of consecutive AA THAs demonstrates an acceptable risk profile within the first 90 days after surgery.


Subject(s)
Arthroplasty, Replacement, Hip/methods , Femoral Fractures/epidemiology , Postoperative Complications/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/adverse effects , California/epidemiology , Female , Femoral Fractures/etiology , Femur/surgery , Hip Joint/surgery , Humans , Male , Middle Aged , Peroneal Neuropathies , Postoperative Complications/etiology , Postoperative Period , Retrospective Studies , Sciatic Neuropathy , Young Adult
2.
Orthopedics ; 38(10): e929-33, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26488790

ABSTRACT

Bleeding from the superior gluteal (SG) blood vessels at the greater sciatic notch is frequently encountered during acetabular fracture surgery. The purpose of this study is to define the positional anatomy of the superior gluteal vessels and nerve (SGVAN) at the greater sciatic notch. Twenty-three hemipelvi were dissected in whole human cadavers. The greater sciatic notch and SGVAN were visualized via a posterior surgical approach, identified deep in the greater sciatic notch, and traced superficially. Branches of the SGVAN and their anatomical relationship to each other were recorded. In the notch, SG arteries comprised a single vessel in 18 (78%) of 23 specimens, with all of these dividing at varying distances (1-3.5 cm) along the lateral ilium after dividing into superior and inferior branches. The SG artery branches were contiguous with periosteum of the bony notch in all specimens. More than 1 SG nerve branch was seen in the greater sciatic notch of all specimens, including an inferior branch that exited caudal or caudal-superficial to the SG vessels. The caudal-most SG nerve branch was directly adjacent to the bony notch's periosteum in 15 (65%) of 23 specimens. The SGVAN are at risk in patients undergoing acetabular fracture surgery. Individuals performing surgery along the acetabulum's posterior column would expect to encounter a major SG nerve branch (deep inferior) before encountering the SG vessels in all cases. Iatrogenic injuries to the SGVAN might be prevented by avoiding use of cautery in this area if hemorrhage is encountered.


Subject(s)
Acetabulum/surgery , Arteries/anatomy & histology , Blood Loss, Surgical/prevention & control , Buttocks/blood supply , Fractures, Bone/surgery , Ilium/anatomy & histology , Orthopedic Procedures/adverse effects , Peripheral Nerve Injuries/prevention & control , Peripheral Nerves/anatomy & histology , Veins/anatomy & histology , Acetabulum/injuries , Adult , Aged , Aged, 80 and over , Arteries/injuries , Buttocks/innervation , Cadaver , Female , Humans , Iatrogenic Disease/prevention & control , Ilium/surgery , Lumbosacral Plexus/anatomy & histology , Male , Middle Aged , Peripheral Nerve Injuries/etiology , Veins/injuries
3.
Patient Saf Surg ; 8: 32, 2014.
Article in English | MEDLINE | ID: mdl-25473418

ABSTRACT

Robert Judet first performed hip arthroplasty via the anterior approach (AA) in 1947 on an orthopaedic table. Our center has a near 20-year experience on more than 3500 patients operated by AA hip arthroplasty. While primary AA total hip arthroplasty techniques have been discussed in the literature, revision AA total hip arthroplasty techniques are relatively new. The current article in the Journal's "Safe Surgical Technique" series describes the successful application of an adjunctive iliac osteotomy to improve femoral exposure in two selected patients undergoing AA revision hip arthroplasty. The potential risk/complications of an iliac osteotomy include iatrogenic fracture, malunion/nonunion, infection, and pain. These potential risks should be weighed against the potential benefits of improved surgical exposure and/or risks of other revision techniques. Future prospective longitudinal studies will be helpful to determine efficacy and risk profile compared to other revision techniques.

4.
Patient Saf Surg ; 8(1): 40, 2014.
Article in English | MEDLINE | ID: mdl-25298784

ABSTRACT

Reconstruction of critical-size bony defects remains a challenge to surgeons despite recent technological advances. Current treatments include distraction osteogenesis, cancellous autograft, induced membranes (Masquelet procedure), polymeric membranes, and titanium-mesh cages filled with bone graft. In this article, the authors presents two cases in which critical-sized defects were reconstructed using a meshed fascial autograft encasing reamer-irrigator-aspirator (RIA) autograft and cancellous allograft. This article will discuss the clinical outcomes of the technique, comparison to other current techniques, and technical insight into the potential biological mechanism.

5.
Am J Orthop (Belle Mead NJ) ; 40(4): 179-82, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21731926

ABSTRACT

This article describes the case of a 39-year-old man who sustained both a lateral process and posteromedial tubercle talus fracture. Both fractures were treated with open reduction and internal fixation resulting in a satisfactory clinical outcome. Although this combination of injuries has been described in the literature, this is the first reported case to describe surgical fixation of both fractures.


Subject(s)
Ankle Injuries/surgery , Ankle Joint/surgery , Fractures, Bone/surgery , Talus/injuries , Talus/surgery , Adult , Ankle Injuries/diagnostic imaging , Ankle Joint/diagnostic imaging , Fracture Fixation, Internal , Fractures, Bone/diagnostic imaging , Humans , Male , Radiography , Recovery of Function , Talus/diagnostic imaging
6.
Patient Saf Surg ; 2: 1, 2008 Jan 14.
Article in English | MEDLINE | ID: mdl-18271949

ABSTRACT

Osteogenesis imperfecta is a genetic disorder characterized by increased susceptibility to fractures and vascular injuries due to connective tissue fragility. In this case report, we present a patient with osteogenesis imperfecta type I who sustained a transverse fracture of the right acetabulum while transferring from bed to chair. The fracture was repaired through an ilioinguinal approach. During the surgery, an iatrogenic injury to the femoral artery and vein occurred. This intraoperative complication was salvaged by immediate vascular repair. We discuss the possible causes of iatrogenic vascular injuries in patients with osteogenesis imperfecta. Orthopaedic surgeons should be aware of this potentially devastating complication in this particular patient cohort.

7.
Patient Saf Surg ; 1(1): 6, 2007 Dec 17.
Article in English | MEDLINE | ID: mdl-18271999

ABSTRACT

Fractures of the pelvic ring have been well studied, and the biomechanical relationship between the anterior and posterior elements is an important concept to understand these complex injuries. The vast majority of these injuries are due to trauma. However, in rare circumstances, autogenous bone graft harvesting may lead to an unstable pelvic ring. In this case report, we describe a rare complication in a 70-year old female patient who developed an unstable pelvis and an infected non-union secondary to repeated posterior iliac graft harvest. The orthopaedic surgeon should be aware of this detrimental complication associated with extensive or repeated posterior iliac crest graft harvest.

8.
Biochem Biophys Res Commun ; 328(3): 764-76, 2005 Mar 18.
Article in English | MEDLINE | ID: mdl-15694412

ABSTRACT

Regulation of chondrogenesis and chondrocyte maturation by prostaglandins has been a topic of interest during recent years. Particular focus on this area derives from the realization that inhibition of prostaglandin synthesis with non-steroidal anti-inflammatory drugs could impact these cartilage-related processes which are important in skeletal development and are recapitulated during bone healing either post-trauma or post-surgery. In addition to reviewing the relevant literature focused on prostaglandin synthesis and signaling through the G-protein coupled EP receptors, we present novel findings that establish the expression profile of EP receptors in chondroprogenitors and chondrocytes. Further, we begin to examine the signaling that may be involved with the transduction of PGE2 effects in these cells. Our findings suggest that EP2 and EP4 receptor activation of cAMP metabolism may represent a central axis of events that facilitate the impact of PGE2 on the processes of mesenchymal stem cell commitment to chondrogenesis and ultimate chondrocyte maturation.


Subject(s)
Chondrocytes/cytology , Chondrocytes/metabolism , Chondrogenesis/physiology , Dinoprostone/pharmacology , Gene Expression Regulation/physiology , Mesenchymal Stem Cells/metabolism , Receptors, Prostaglandin E/metabolism , Aging/drug effects , Aging/metabolism , Animals , Cell Differentiation/drug effects , Cell Differentiation/physiology , Cells, Cultured , Chondrocytes/drug effects , Chondrogenesis/drug effects , Cyclic AMP/metabolism , Dose-Response Relationship, Drug , Gene Expression Regulation/drug effects , Gestational Age , Limb Buds , Mesenchymal Stem Cells/cytology , Mesenchymal Stem Cells/drug effects , Mice , Protein Isoforms/metabolism
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