Perforation of congenitally deformed aortic valve resulting in aortic insufficiency. Report of case successfully treated by aortic valve replacement.

This 40-year-old male presented with the signs and the symptoms of acute aortic insufficiency and underwent aortic valve replacement. At surgery a deformed aortic valve with perforation was found. This represents a unique example of a congenitally deformed aortic valve complicated by acute perforation with resultant valvular incompetence.

Right ventricular metastatic melanoma 27 years after resection of the primary tumor.

This article is a case report of a 65-year-old white woman with a history of malignant melanoma, resected from her back in 1959. She presented 27 years later with right-sided heart failure and metastatic melanoma to her right ventricle. To the authors' knowledge, a large ventricular mass as the sole site of disease recurrence has not been described previously.

Healing of laser-induced defects of articular cartilage: preliminary studies.

The investigators have induced defects to the articular surfaces of knee joints in rabbits with the use of a CO2 laser. Subsequent healing of these defects have been studied and are described. This work has demonstrated healing with formation of fibrocartilage and hyaline cartilage in two of eight cases. Further investigation with improved techniques will be undertaken in order to produce effective healing on a more consistent basis. This article also reviews previous investigation related to the healing of cartilage defects.

Papillary cystic neoplasm of the pancreas: report of two cases of a surgically curable tumor.

This is a report of two cases of papillary cystic neoplasm of the pancreas, a recently described, relatively benign tumor of the pancreas that occurs predominantly in young women. The clinical presentation, radiographic features, and gross and microscopic pathologic findings along with immunohistochemical and electron microscopic studies are described. A brief review of the literature is cited and surgical significance is discussed.

Superficial laser vulvectomy. II. The anatomic and biophysical principles permitting accurate control over the depth of dermal destruction with the carbon dioxide laser.

The rationale for using the carbon dioxide laser to treat either vulvar intraepithelial neoplasia or extensive papillomaviral infections is to destroy the entire area of abnormal epithelium to a shallow depth, so that rapid healing will occur from normal keratinocytes in the underlying pilosebaceous glands. After the first laser impact, anatomic landmarks in the crater base are disguised by a layer of charred proteins, and any structure that is visible will already have suffered thermal necrosis. Accurate control of depth depends upon special surgical strategies that correlate the level of the underlying zone of thermal necrosis with specific visual appearances within the zone of vaporization. Maneuvers that limit depth of penetration to one of three desirable surgical planes (basement membrane, papillary dermis, midreticular dermis) are described.

Adenocarcinoid of appendix presenting as bilateral ovarian tumors. A case report with histochemical and ultrastructural studies.

A 62-year-old female presented with bilateral ovarian tumors. These proved to be metastatic from a primary appendiceal lesion which showed histochemical and ultrastructural evidence of differentiation along two cell lines with features of both carcinoid and mucinous tumor. This case illustrates the malignant potential of so-called mucinous carcinoid or adenocarcinoid of the appendix.