[Malignant melanoma in dermatoscopical picture]. / Maligní melanom v dermatoskopickém obrazu (Informacní sdelení).

Dermatological investigation offers a more precise clinical diagnosis of malignant melanoma in 20-30% of cases. It gives a correct visualization of melanocytic structures up to dermatoepidermal junction in ten fold magnification. A less distinct picture can be obtained from medium corial structures. Lentigo maligna melanoma and superficially spreading melanoma can be well distinguished from other pigmented lesions. Dermatoscopy offers an inspirative view between a clinical and microscopical picture plane.

Lichen ruber and bullous pemphigoid.

The authors describe the case of a male patient, 20 years old, with a rapidly developing picture of disseminated lichen ruber planus together with the formation of vesicles and blisters. Immunofluorescent examination demonstrated lichen ruber associated with bullous pemphigoid. A good therapeutic effect was obtained with a combination of Triamcinolon and Tigason.

[The importance of immunofluorescence methods in dermatology]. / Význam imunofluorescencních vysetrovacích metod v dermatologii.

An immediate significance of detection of antibodies by fluorescence distinguish pemphigus, pemphigoid, herpetiform dermatitis and erythematodes. In vasculi-immunohistology was reviewed for diagnostic dermatopahology. Immunohistology helped to tides and lichen ruber planus there were findings more difficult for diagnostis but stimulating.

Benign hypergammaglobulinemic purpura in a patient with ulcerative colitis and peripheric arthritis.

A 32-year-old patient is described presenting with ulcerative colitis and oligoarthritis who later developed benign hypergammaglobulinemic purpura. This diagnosis was confirmed by clinical investigation, immunological findings as well as by histological and immunofluorescent examination. He was successfully treated with steroids and azathioprin. The relevant literature is reviewed.