ABSTRACT
OBJECTIVE: Diffuse glioma arises anywhere in the CNS, but most frequent in the cerebral hemispheres. The tumor tends to be seen in children and in younger adults aged 20-30. We report one such case in an older female patient presenting the intraoperative cytology of the tumor. CASE REPORT: A 48-year-old female was diagnosed by MRI with a tumor of cerebellum. Cytologic material was obtained during the resection of the tumor and diagnosed cytologically as glioma. CONCLUSION: This case is presented to focus the ability of the intraoperative cytology in diagnosis of the glioma, using immunocytology and confirmed by histo- immunohistology.
Subject(s)
Glioma , Adult , Cerebellum/diagnostic imaging , Cerebellum/pathology , Child , Cytodiagnosis , Female , Glioma/diagnostic imaging , Glioma/pathology , Humans , Magnetic Resonance Imaging , Middle AgedABSTRACT
Schwannomas affect mainly head and neck peripheral nerves, are benign tumors and derive from Schwann cells. Schwannoma of right cerebellopontine angle is extremely rare to diagnose by cytology. We report one such rare case presenting the cytological features in material obtained during the resection of the tumor. Case report: A 47-year-old female was diagnosed by MRI with a tumor of right cerebellopontine angle.. Cytologic material from the tumor was obtained intraoperatively and diagnosed cytologically as a neurilemoma. Conclusion: This case is presented here to focus the ability of cytology in diagnosis of schwannoma in intraoperative material of the tumor, using immunohistochemistry and confirmed by histology- immunohistochemistry.
Subject(s)
Cerebellar Neoplasms/diagnosis , Cerebellopontine Angle/pathology , Neurilemmoma/diagnosis , Biomarkers, Tumor , Cerebellar Neoplasms/diagnostic imaging , Cerebellar Neoplasms/pathology , Cerebellar Neoplasms/surgery , Cerebellopontine Angle/diagnostic imaging , Cerebellopontine Angle/surgery , Female , Humans , Immunohistochemistry , Magnetic Resonance Imaging , Middle Aged , Neurilemmoma/diagnostic imaging , Neurilemmoma/pathology , Neurilemmoma/surgeryABSTRACT
Small cell glioblastoma is a high anaplastic variant of GBM characterized by a monomorphic proliferation of small or medium cells with oval nuclei and scanty cytoplasm. CASE STUDY: The cytologic findings of a small cell glioblastoma in 11-year-old male and histologic features of the tumor using immunocytohistochemistry are reported. CONCLUSION: The accurate preoperative diagnosis of a small cell glioblastoma is crucial to developing a curative surgical plan. Cytology- confirmed by histology- provides a convenient, safe and effective approach to solving a challenging differential diagnosis.
