[Lipid metabolism disorders in white rats following depression of the anticlotting system by an atherogenic diet]. / Narusheniia lipidnogo obmena u belykh krys pri depressii protivosvertyvaiushchei sistemy aterogennoi dietoi.

Experiments conducted with adult rats kept on an therogenic diet for 30 and 45 days demonstrated that with depressed function of the anticoagulation system and developing prethrombotic state of the organism there occur changes in the spectrum of the animals blood serum lipoproteids, namely--an increase of the pre-beta-lipoproteids fraction, the appearance of the chylomicrones fraction and a fall-off of the alpha-lipoproteids fraction. The total content of atherogenic lipoproteids (beta- and pre-beta-lipoproteids) rises by as much as 2-4 times. The depression of the anticoagulation function stemming from alimentary lipemia comes as a menace of forthcoming intravascular thrombogenesis.