ABSTRACT
Methodological recommendations for surgical care in patients with hemophilia A receiving prophylactic therapy with emicizumab. Recommendations of the expert group. Moscow, 2024.
Subject(s)
Antibodies, Bispecific , Antibodies, Monoclonal, Humanized , Hemophilia A , Humans , Hemophilia A/complications , Hemophilia A/drug therapy , Factor VIII , Hemorrhage/prevention & control , Antibodies, Bispecific/adverse effectsABSTRACT
The article presents a case of a surgical treatment of removing a dermoid cyst of the floor of the oral cavity in a patient with severe hemophilia A. A detailed analysis was carried out of the surgical operation, postoperative management, coagulation factor replacement therapy and accompanying therapy, as well as the features of anesthesia, which allowed a surgical intervention without any hemorrhagic and infectious complications.
Subject(s)
Anesthesia, Dental , Dermoid Cyst , Hemophilia A , Mouth Neoplasms , Humans , Mouth Neoplasms/complications , Mouth Neoplasms/surgery , Dermoid Cyst/complications , Dermoid Cyst/surgery , Hemophilia A/complications , Mouth Floor/surgeryABSTRACT
AIM: The aim of the study was to describe the use of the wound analgesia method in a patient with hemophilia in the case of a clinical case. MATERIALS AND METHODS: A patient with severe hemophilia A underwent postoperative analgesia after total knee replacement (within the first 48 hours) with an extended infusion of local anesthetic (ropivacaine) into the wound. RESULTS: During the first 8 hours, the patient received 20 mg of morphine (with the aid of a device for patient-controlled analgesia), the pain level ranged from 7 to 4 points. Further, there was a sufficient effect (NRS - 2 points), from anesthesia only with ropivacaine, using a system for anesthetizing surgical wounds. Complications and side effects were not noted. CONCLUSION: The clinical case demonstrates an effective and safe method of prolonged analgesia in patients with hemophilia. Considering encouraging data, further study of wound analgesia in this category of patients is necessary.
