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Ukr Biokhim Zh (1978) ; 65(4): 78-82, 1993.
Article in Ukrainian | MEDLINE | ID: mdl-8284826

ABSTRACT

The existence of enzymatic NADH-dependent peroxidation of lipids has been established. Some its characteristics in comparison with nonenzymatic ascorbate-dependent and enzymatic NADPH-dependent lipid peroxidation have been found. Some reactions of enzymatic peroxidation of lipids (NADPH- and NADH-dependent) in contrast to nonenzymatic (ascorbate-dependent), is not inhibited by the electron carriers (methylene blue and vikasol). This part of lipid peroxidation is not affected by hypoxia and combined effect of hypoxia as well as the action of carbon oxide (II) both separate and in combination with the electron carriers.


Subject(s)
Lipid Peroxidation/physiology , NAD/metabolism , Animals , Cytochrome P-450 Enzyme System/biosynthesis , Electron Transport , Enzyme Inhibitors , Rats , Substrate Specificity
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