ABSTRACT
BACKGROUND: Nonunions of the tibia represent challenging orthopedic problems, which require the surgeon to analyze numerous factors and choose an appropriate treatment. This article presents a case report of tibia and fibula fracture patient who failed the internal fixation surgery and successfully recovered after one course of percutaneous autologous platelet lysates injection. CASE DESCRIPTION: The patient received an internal nickelclad breakage at 9 months post-surgery but reluctant to accept a second surgery, then autologous platelet lysates (APL) injection which is a less invasive method was recommended. The injections were carried once a week for three times. Radiologic evaluation was conducted every month until recovery. DISCUSSION AND EVALUATION: To the best of our knowledge, this is the first reported case of tibia delayed union with breakage of the plate resolved with APL injection. Improved clinical evidence was observed at 4 and 6 months after injection. The patient got good bony union at 8 months post-injection. The patient didn't feel any discomfort postinjection, no complications such as infection, refracture etc. were observed. CONCLUSIONS: APL percutaneous injection could be a new therapeutic option for the treatment of nonunion or delayed healing fractures.
ABSTRACT
BACKGROUND: The purpose of this study was to investigate the efficacy and safety of autologous platelet lysate (APL) local injections in reducing pain and improving function in patients with refractory lateral epicondylitis. METHODS: A total of 56 patients with refractory lateral epicondylitis were enrolled in this study. All the patients received three injections in one course of treatment. Subjective assessments include visual analog scale (VAS) pain score and Mayo elbow score before injection (baseline) and at 1, 6, and 12 months after injection. RESULTS: Significant differences were observed in VAS and Mayo scores at baseline and at 1, 6, and 12 months after injection. Overall, the injections of APL improved local symptoms and all the patients recovered to normal elbow function with 12 months follow-up. CONCLUSIONS: Local injections of APL resulted in favorable clinical outcomes for the treatment of lateral epicondylitis. APL could be clinically effective in the treatment of lateral epicondylitis.
Subject(s)
Blood Platelets , Tennis Elbow/therapy , Adult , Elbow Joint/diagnostic imaging , Elbow Joint/physiopathology , Female , Follow-Up Studies , Hand Strength , Humans , Injections, Intra-Articular , Male , Middle Aged , Pain Measurement/methods , Range of Motion, Articular , Tennis Elbow/diagnostic imaging , Tennis Elbow/physiopathologyABSTRACT
Tunable diode laser absorption spectroscopy technology (TDLAS), with its advantages of high selectivity and accuracy, provides a reliable approach to the on-line detection of escaping ammonia. Firstly, the present paper introduces the TDLAS principle, experimental system and the analyses of system noise. Then with the concentration of 90 x 10(-6) and 30 x 10(-6) NH3 for example, we used TDLAS system to collect their second harmonic original spectrum with all kinds of noise interference. To improve the signal spectrum, five types of digital filtering methods were respectively used to filter the original spectrum. Finally we did the NH3 experiments of concentration gradient and the long time monitoring: NH3 experiment of 20 x 10(-6). The analysis indicated that the averaging-wavelet filtering is validated to be more accurate than the other filtering methods in the noise reduction, which can improve the precision of the monitoring system from 10 x 10(-6) to 1.25 x 10(-6) and the SNR also increases by 14 times. It provides an effective pretreatment during the monitoring of escaping ammonia of extremely low concentration.
ABSTRACT
Moisture, as a core determination of the economic value of coal, can result in the utilization and energy inefficiency. Near-infrared (NIR) spectroscopy, with advantages of high accuracy and low cost, provides significant solution to the quick and non-invasive detection of coal moisture. In the present paper, the improvement of the coal moisture analysis was conducted based on the precision of 1% and insufficient comparisons in recent experiments, and aspects of spectrum pretreatment and wavelength selection were mainly discussed. The optimized result with R-square of 0.995, RMSEC of 0.06% and RMSEP of 0.27% indicates the priority of wavelet decomposition and reconstruction, compared with other methods, in the noise reduction and baseline removing of original spectra (1 300-2 400 nm) before PLS modeling, and the stability experiment validates its robust potential in improving precision of coal moisture detection based on the NIR spectroscopy.
