ABSTRACT
Objective: To explore the relationship between the hepatic caudate lobe boundary and the ductal system so as to guide the identification of the anatomical relationship during liver surgery. Methods: The specific parts were observed and the liver parenchyma was removed according to 41 cadaveric liver autopsy specimens. The critical relationship between the hepatic caudate lobe and other ducts was observed to explore the reticular duct structure. Results: The plane formed by the hepatic hilar plate and Arantius ligament served as the boundary between the caudate lobe and other hepatic lobes. The caudate lobe hepatic portal vein was composed of numerous small branches from its left and right branches. The portal vein adjacent to the vena cava was mainly derived from the left branch, and to a lesser extent from the right branch. Blood was drained straight from the caudate lobe vein into the inferior vena cava via the short hepatic vein. There were three or four bile duct branches in the caudate lobe. The main source of arterial blood flow were the left and right branches of the hepatic artery. An avascular zone of loose connective tissue was found between the caudate lobe and the retrohepatic inferior vena cava. Conclusion: The hepatic caudate lobe is an independent lobe. During hepatic caudate lobe surgery, the plane formed by the hepatic hilar plate and Arantius ligament can serve as the boundary between the caudate lobe and other hepatic lobes and be used for anatomical site identification. The duct system of the caudate lobe's is complicated, but it also has its own distinct regularity.
Subject(s)
Hepatic Artery , Liver , Humans , Liver/blood supply , Bile Ducts , Portal Vein , Hepatic Veins , HepatectomyABSTRACT
Confirmed the full-length sequence of HLA-C*15:13:01:01 by cloning and sequencing in a Chinese donor.
Subject(s)
HLA-C Antigens/genetics , Base Sequence , Exons/genetics , Humans , Sequence Analysis, DNAABSTRACT
Confirmed the full-length sequence of HLA-C*03:02:01 by cloning and sequencing in a Chinese donor.
Subject(s)
Alleles , HLA-C Antigens/genetics , Base Sequence , Humans , Introns/geneticsABSTRACT
Confirmed the full-length sequence of HLA-C*03:40:01 by cloning and sequencing in a Chinese donor.
Subject(s)
Alleles , HLA-C Antigens/genetics , Base Sequence , Exons/genetics , Humans , Introns/geneticsABSTRACT
The fulllength sequence of HLAB*59:01:01:01.
Subject(s)
HLA-B Antigens/genetics , Sequence Analysis, DNA , Alleles , Asian People/genetics , Base Sequence , Cloning, Molecular , HumansABSTRACT
Confirmed the full-length sequence of HLA-B*44:03:02 by cloning and sequencing in a Chinese donor.
Subject(s)
Cloning, Molecular , HLA-B44 Antigen/genetics , Sequence Analysis, DNA , HumansABSTRACT
Full-length sequences of HLA-B*48:03:01 and B*48:04:01, confirmed by cloning and sequencing in Chinese donors.
Subject(s)
Cloning, Molecular , HLA-B Antigens/genetics , Sequence Analysis, DNA , Asian People , HumansABSTRACT
Full-length sequences of HLA-B*40:01:01, B*40:03 and B*40:40, confirmed by cloning and sequencing in Chinese donors.
Subject(s)
Alleles , Exons , HLA-B40 Antigen/genetics , Polymorphism, Genetic , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , HLA-B40 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
Full-length sequences of HLA -B*27:04:01, B*27:07:01 and B*27:25, confirmed by cloning and sequencing in Chinese donors.
Subject(s)
Alleles , Exons , HLA-B27 Antigen/genetics , Polymorphism, Single Nucleotide , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , Genotype , HLA-B27 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNA , Tissue DonorsABSTRACT
Full-length sequences of HLA-B*07:05:01:01, B*14:01:01 and B*18:02, confirmed by cloning and sequencing in Chinese donors.
Subject(s)
Alleles , Exons , HLA-B14 Antigen/genetics , HLA-B18 Antigen/genetics , HLA-B7 Antigen/genetics , Polymorphism, Genetic , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , HLA-B14 Antigen/immunology , HLA-B18 Antigen/immunology , HLA-B7 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNA , Tissue DonorsABSTRACT
We report the full-length sequences of 4 alleles of the HLA-B*15 gene family.
Subject(s)
Alleles , Exons , HLA-B15 Antigen/genetics , Polymorphism, Genetic , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , HLA-B15 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
Full-length sequences of 4 alleles of HLA-B*35 gene family, confirmed by cloning and sequencing.
Subject(s)
Alleles , Exons , HLA-B35 Antigen/genetics , Polymorphism, Genetic , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , HLA-B35 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
Full-length sequences of HLA-B*67:01:01 and B*67:01:02, confirmed by cloning and sequencing from Chinese donors.
Subject(s)
Alleles , Exons , HLA-B Antigens/genetics , Polymorphism, Genetic , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , HLA-B Antigens/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
We report the full-length sequence of 4 HLA-B*15 alleles, B*15:07:01:01, B*15:27:01, B*15:32:01 and B*15:58.
Subject(s)
Alleles , Exons , HLA-B15 Antigen/genetics , Polymorphism, Genetic , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , HLA-B15 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
Full-length sequence of HLA-B*55:02:01:01, confirmed by cloning and sequencing in a Chinese donor.
Subject(s)
Alleles , Exons , HLA-B Antigens/genetics , Polymorphism, Single Nucleotide , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , Genotype , HLA-B Antigens/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
Full-length sequences of HLA-B*39:05:01 and B*39:38Q , confirmed by cloning and sequencing in Chinese donors.
Subject(s)
Alleles , Base Sequence , Exons , HLA-B39 Antigen/genetics , Mutagenesis, Insertional , Sequence Deletion , Asian People , Cloning, Molecular , Codon/chemistry , Gene Expression , Genotype , HLA-B39 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Introns , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNA , Tissue DonorsABSTRACT
Full-length sequences of HLA-B*56:01:01:01, B*56:03 and B*56:04, confirmed by cloning and sequencing in Chinese donors.
Subject(s)
Alleles , Exons , HLA-B Antigens/genetics , Introns , Polymorphism, Genetic , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , Genotype , HLA-B Antigens/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Polymerase Chain Reaction , Protein Isoforms/genetics , Protein Isoforms/immunology , Sequence Alignment , Sequence Analysis, DNAABSTRACT
Full-length sequence of HLA-B*52:01:01:01 and B*52:01:02:01, identified by cloning and sequencing in Chinese donors.
Subject(s)
Alleles , Exons , HLA-B52 Antigen/genetics , Polymorphism, Single Nucleotide , Tissue Donors , Asian People , Base Sequence , Cloning, Molecular , Codon/chemistry , Gene Expression , Genotype , HLA-B52 Antigen/immunology , Hematopoietic Stem Cell Transplantation , Histocompatibility Testing , Humans , Polymerase Chain Reaction , Sequence Alignment , Sequence Analysis, DNAABSTRACT
HLA-DQB1*03:01:34 has one nucleotide change from HLA- DQB1*03:01:01 at nucleotide 357 bp where C>A in exon 2.
ABSTRACT
HLA-B*15:374 has one nucleotide change from HLA-B*15:02:01 at nucleotide 553 bp where G â A in exon 3.
