[The prevalence of idiopathic proctocolitis]. / K otázce prevalence idiopatické proktokolitidy.

During screening of colorectal cancer by the Haemoccult test (Röhm Pharma Co.) the authors investigated the incidence of idiopathic proctocolitis in the population of the Bruntál district. The group of tested subjects comprises 16.642 of the population aged 45 to 86 years. After examination of 380 positive subjects (2.28%) twelve cases of idiopathic proctocolitis were detected. Of these twelve seven were identified previously and a new diagnosis was made in five subjects. At twelve cases were identified from a population of 16.642, the assumed prevalence in 1989 in the given age group is 72/100.000. This suggests considerable underestimation of the prevalence of idiopathic proctocolitis in current epidemiological surveys.

[Problems in the early diagnosis and treatment of colorectal carcinoma and adenoma in the aged]. / Problematika vcasné diagnózy a lécby kolorektálního karcinomu a adenomu ve stárí.

In 1985-1989 in the Bruntál district by means of the test for occult haemorrhage (Haemoccult, Röhm Pharma Co.) a total of 1084 subjects aged 65-86 years were examined. The test was positive in 74 subjects (6.83%). A subsequent coloscopic examination was made in 60 subjects, 81% of those with a positive test. Coloscopic examination revealed 8 patients with carcinoma of the large intestine and 45 patients with an adenomatous polyp. The oncological positivity is thus 4.89% of the tested subjects and 88.33% of those subjected to coloscopy. The carcinoma was evaluated in two cases in the stage Dukes A, in four instances in stage Dukes B, in one case in stage Dukes C and in one case in stage Dukes D. In two patients with carcinoma another adenomatous polyp was found in the large intestine. In 14 patients of 45 with an adenomatous polyp another synchronous adenomatous polyp was detected (31.1%). 43 patients were treated by coloscopic polypectomy. Contemporary possibilities of early diagnosis of colorectal carcinoma in conjunction with effective therapeutic endoscopy are perspective in particular in patients of advanced age.

Results of screening for colorectal carcinoma in the District of Bruntál using the Haemoccult Test in 1985-1988.

In 1985-1988, 11,046 working people of the district of Bruntál, aged 45-69, were examined for occult bleeding into the stools, using the Haemoccult test. The return rate of the tests was 92.05%. Screening detected 241 patients (2.18%) with positive stools test results who were referred to further examination. 129 patients (1.17%) were found to have one or more adenomatous polyps or adenocarcinoma in the large intestine. Adenocarcinoma was detected in 15 cases (0.13%): eight in stage Dukes A, two in stage Dukes B, three in Dukes C, and two in Dukes D stages. Endoscopic polypectomy or surgical operation were used for treatment. The programme of screening for colorectal carcinoma as elaborated for the low-risk group of asymptomatic subjects over 45 years of age helps to detect less advanced stages of this oncological affection.

[Results of screening for colorectal carcinoma in the Bruntál District using the Haemoccult Test 1985-1986]. / Výsledky depistáze kolorektálního karcinomu v okrese Bruntál Haemoccult testem v letech 1985-1986.

In the Bruntál district in 1985-1986 in 11,046 working people aged 45-69 years an examination for occult haemorrhage into faeces was made, using the Haemoccult test. The return rate of the tests was 92.05%. Screening detected 241 patients (2.18%) with positive tests in faeces, who were subjected to further examinations. In 129 patients (1.17%) one or more adenomatous polyps or adenocarcinoma of the large intestine was proved. Adenocarcinoma was detected in 15 (0.13%), eight times in stage Dukes A, twice Dukes B, three times Dukes C and twice Dukes 2. Treatment involved endoscopic polypectomy or surgical operation. Tre elaborated screening programme of colorectal carcinoma for a low risk group of asymptomatic subjects above 45 years of age helps to detect less advanced stages of this oncological affection.

[Repeat screening for colorectal carcinoma in a population of asymptomatic individuals after 2 years]. / Opakovaná depistáz kolorektálního karcinomu v populaci asymptomatických jedincu po dvou letech.

The first stage of the screening of colorectal carcinoma took place in the Bruntál district in 1985-1986. In 1987-1988 this population group of asymptomatic workers was examined repeatedly. After two years an examination of 4512 subjects from a total of 4909 issued tests was made. During the repeated screening programme the return rate of tests was 91.9%. The number of patients with positive occult haemorrhage into faeces was 65 (1.44%). The number of patients with positive oncological disease in the sense of an adenomatous polyp or carcinoma was 18 (0.40%). None of these 18 patients was in the group of patients with positive occult haemorrhage in the first stage of the screening in 1985-1986. Adenocarcinoma was revealed in two instances, once in stage Dukes A and once in stage Dukes B. Another cause of positivity of occult haemorrhage in faeces was diagnosed in 47 cases (1.04%). The frequency of oncologically conditioned positivity of occult haemorrhage in faces declined during screening after two years from the original 0.92% to 0.40%. Both detected carcinomas of the large intestine were revealed at a time which, if further radical treatment is provided, gives hope of satisfactory therapeutic results.

[Experience with screening for colorectal carcinoma using the Haemoccult Test]. / Zkusenosti s depistází kolorektálního karcinomu Haemoccult testem.

The authors submit their experience with the screening of colorectal cancer in 1985-1987 in the Bruntál district. Within the programme 9772 workers from industry and agriculture aged 45 years and more, regardless of sex, were examined. The return rate of tests was 93% and a total of 189 patients with a positive test of occult haemorrhage (1.93%) was detected. Adenomatous polyps or colorectal carcinoma were diagnosed in 91 patients (0.93%). The authors discuss demands which must be respected to make the screening successful. Attention is focused not only on the activity of health workers in this preventive programme but also to help leading workers in enterprises and the lay public. Only by coordination of the activities of all these bodies a favourable effects can be achieved.